Current reprogramming systems in regenerative medicine: from somatic cells to induced pluripotent stem cells

C Hu, L Li - Regenerative medicine, 2016 - Taylor & Francis
Induced pluripotent stem cells (iPSCs) paved the way for research fields including cell
therapy, drug screening, disease modeling and the mechanism of embryonic development …

Method to assemble genomic DNA fragments or genes on human artificial chromosome with regulated kinetochore using a multi-integrase system

NCO Lee, JH Kim, NS Petrov, HS Lee… - ACS Synthetic …, 2017 - ACS Publications
The production of cells capable of carrying multiple transgenes to Mb-size genomic loci has
multiple applications in biomedicine and biotechnology. In order to achieve this goal, three …

诱导性多能干细胞治疗: 移植排斥与安全性问题

吴鹏飞, 周光纪 - 中国组织工程研究, 2015 - cjter.com
背景: 诱导性多能干细胞自发现以来一直是再生医学的研究热点, 但人们过多地关注了它的运用
性却忽略了安全性. 目的: 通过综述目前诱导性多能干细胞在动物移植研究中的表现 …

[PDF][PDF] IN VITRO DIFFERENTIATION OF WHARTON'S JELLY-DERIVED IN VITRO DIFFERENTIATION OF WHARTON'S JELLY-DERIVED IN VITRO …

M Kerékgyártó, AJ Szalai, E Kiss-Tóth, O Rácz… - Egeszsegtudomanyi …, 2019 - matarka.hu
Diabetes mellitus is one of the major chronic metabolic disorders characterized by
progressive destruction of insulin-producing beta cells in the pancreatic islets of …

Induced pluripotent stem cell therapy: transplant rejection and safety

P Wu, G Zhou - Chinese Journal of Tissue Engineering Research, 2015 - cjter.com
BACKGROUND: Induced pluripotent stem cells have been a hotspot in regenerative
medicine research since it was discovered. The clinical application of induced pluripotent …

[PDF][PDF] The octamer-binding transcription factor 4 (Oct-4) and stem cell literatures

M Hongbao, M Young - Citeseer
The octamer is made of eight units. The octamer-binding transcription factor 4 (Oct-4) is a
protein also known as POU5F1 (POU domain, class 5, transcription factor 1) encoded by the …

[引用][C] BMSCs 旁分泌对软骨细胞IL-1β 损伤后的保护作用

徐立璋, 邓国英, 王伟恒, 黄晓东, 杨向群, 叶晓健 - 中国修复重建外科杂志, 2015

[引用][C] Klf4 and stem cell literatures

M Hongbao, M Young - Tissue Eng Part A, 2014