Genome-wide association studies (GWAS) test hundreds of thousands of genetic variants
across many genomes to find those statistically associated with a specific trait or disease …

Genome-wide association studies have identified hundreds of robust genetic associations
underlying psychiatric disorders and provided important biological insights into disease …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

A major focus of academia, industry, and global governmental agencies is to develop and
apply artificial intelligence and other advanced analytical tools to transform health care …

There exist limited data to inform mechanism-based understanding and management of
chronic pain, and thus, there is a clear unmet need to better define the molecular …

Early identification of attention-deficit/hyperactivity disorder (ADHD) is critical for mitigating
the many negative functional outcomes associated with its diagnosis. Because of the strong …

In the second half of the twentieth century, twin and family studies established beyond a
reasonable doubt that all forms of psychopathology are substantially heritable and highly …

Over 90% of drug candidates fail in clinical trials, while it takes 10–15 years and one billion
US dollars to develop a single successful drug. Drug development is more challenging for …

Neuropsychiatric phenotypes have long been known to be influenced by heritable risk
factors, directly confirmed by the past decade of genetic studies that have revealed specific …

Polygenic risk prediction remains an important aim of genetic association studies. Currently,
the predictive power of schizophrenia polygenic risk scores (PRSs) is not large enough to …