Plasma protein (albumin) catabolism by the tumor itself—implications for tumor metabolism and the genesis of cachexia

G Stehle, H Sinn, A Wunder, HH Schrenk… - Critical reviews in …, 1997 - Elsevier
A common feature to all cancers is its growth by parasitizing the host's energy and nutrients.
In the 1920s Warburg and Cori demonstrated the importance of carbohydrate metabolism …

Radiohalogenation of proteins: an overview of radionuclides, labeling methods and reagents for conjugate labeling

DS Wilbur - Bioconjugate chemistry, 1992 - ACS Publications
434 Bioconjugate Chem., Vol. 3, No. 6, 1992 Wilbur easy to use and readily available at a
nominal cost from commercial sources. Other radionuclides of the halogen group, while not …

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs

C Wolfrum, S Shi, KN Jayaprakash, M Jayaraman… - Nature …, 2007 - nature.com
Cholesterol-conjugated siRNAs can silence gene expression in vivo. Here we synthesize a
variety of lipophilic siRNAs and use them to elucidate the requirements for siRNA delivery in …

Initiation of atherosclerotic lesions in cholesterol-fed rabbits. II. Selective retention of LDL vs. selective increases in LDL permeability in susceptible sites of arteries.

DC Schwenke, TE Carew - … : An Official Journal of the American …, 1989 - Am Heart Assoc
We asked if the arterial sites most prone to early lesions in cholesterol-fed rabbits have
higher permeabilities to low density lipoprotein (LDL) in normolipidemic rabbits or if these …

[HTML][HTML] Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

JM Timmins, JY Lee, E Boudyguina… - The Journal of …, 2005 - Am Soc Clin Investig
Patients with Tangier disease exhibit extremely low plasma HDL concentrations resulting
from mutations in the ATP-binding cassette, sub-family A, member 1 (ABCA1) protein …

Apolipoprotein M is required for preβ-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis

C Wolfrum, MN Poy, M Stoffel - Nature medicine, 2005 - nature.com
High-density lipoproteins (HDLs) are considered antiatherogenic because they mediate
reverse cholesterol transport from the periphery to the liver for excretion and degradation …

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein …

TE Carew, DC Schwenke… - Proceedings of the …, 1987 - National Acad Sciences
It has been postulated that low density lipoprotein (LDL) becomes fully atherogenic only if it
first undergoes oxidative modification. The oxidatively modified form, but not native LDL, is …

Dissociation of tissue uptake of cholesterol ester from that of apoprotein AI of rat plasma high density lipoprotein: selective delivery of cholesterol ester to liver, adrenal …

C Glass, RC Pittman, DB Weinstein… - Proceedings of the …, 1983 - National Acad Sciences
The metabolic fate of homologous high density lipoprotein (HDL) was studied in the rat,
tracing the apoprotein AI (apo AI) and cholesterol ester moieties simultaneously. The apo AI …

Saturated and unsaturated fatty acids independently regulate low density lipoprotein receptor activity and production rate.

LA Woollett, DK Spady, JM Dietschy - Journal of lipid research, 1992 - Elsevier
These studies examine the regulation of plasma low density lipoprotein (LDL)-cholesterol
levels by varying quantities of dietary saturated and polyunsaturated triacylglycerols. At a …

Accumulation of lipoprotein fractions and subfractions in the arterial wall, determined in an in vitro perfusion system

T Björnheden, A Babyi, G Bondjers, O Wiklund - Atherosclerosis, 1996 - Elsevier
A large proportion of a dense subfraction of LDL in plasma is coupled with an increased risk
of coronary artery disease, CAD. This may reflect an increased inflow of such LDL …