Despite the significance of efforts to understand the biological basis of autism, progress in
this area has been hindered, in part, by the considerable heterogeneity in the disorder …

Persons with Down syndrome (DS) have reduced peak and submaximal exercise capacity.
Because ambulation is one predictor of survival among adults with DS, a review of the …

Purpose To investigate age-related changes in aerobic capacity in persons with MR, with
and without DS, using a retrospective analysis. Methods Data were collected in university …

Advanced Cardiovascular Exercise Physiology, Second Edition, systematically details the
effects of acute and chronic exercise training on each component of the cardiovascular …

Background Many children with autism and other neurodevelopmental disorders undergo
expensive, time-consuming behavioral interventions that often yield only modest …

Low work capacity and VO 2peak commonly are described phenomena in Down syndrome.
This is accompanied by chronotropic incompetence and a high incidence of obesity …

Persons with Down syndrome (DS) are at high risk for cardiovascular morbidity and
mortality, and there is compelling evidence of autonomic dysfunction in these individuals …

Individuals with Down syndrome present many clinical characteristics, such as metabolic,
endocrine, anatomic and neurologic dysfunctions, that contribute to the physiopathology of …

Summary Down Syndrome (Ds) is the most common chromosomal cause of intellectual
disability that results from triplication of chromosome 21 genes. Individuals with Ds …

Exercise testing plays an increasingly important role in the diagnosis and assessment of
heart disease and lung disease in children and adolescents. In Cardiopulmonary Exercise …