[HTML][HTML] A systematic review on the usage of averaged LET in radiation biology for particle therapy

F Kalholm, L Grzanka, E Traneus, N Bassler - Radiotherapy and Oncology, 2021 - Elsevier
Abstract Linear Energy Transfer (LET) is widely used to express the radiation quality of ion
beams, when characterizing the biological effectiveness. However, averaged LET may be …

A critical review of LET-based intensity-modulated proton therapy plan evaluation and optimization for head and neck cancer management

W Deng, Y Yang, C Liu, M Bues… - … Journal of Particle …, 2021 - meridian.allenpress.com
In this review article, we review the 3 important aspects of linear-energy-transfer (LET) in
intensity-modulated proton therapy (IMPT) for head and neck (H&N) cancer management …

Mechanisms and review of clinical evidence of variations in relative biological effectiveness in proton therapy

H Paganetti - International Journal of Radiation Oncology* Biology …, 2022 - Elsevier
Proton therapy is increasingly being used as a radiation therapy modality. There is
uncertainty about the biological effectiveness of protons relative to photon therapies as it …

Dosimetric analysis of six whole-breast irradiation techniques in supine and prone positions

DW Kim, CS Hong, J Son, SY Kim, YI Park, M Chung… - Scientific Reports, 2024 - nature.com
In breast cancer radiation therapy, minimizing radiation-related risks and toxicity is vital for
improving life expectancy. Tailoring radiotherapy techniques and treatment positions can …

Incorporation of the LETd-weighted biological dose in the evaluation of breast intensity-modulated proton therapy plans

C Liu, D Zheng, JA Bradley, RB Mailhot Vega… - Acta …, 2021 - Taylor & Francis
Abstract Purpose To evaluate the LETd-weighted biological dose to OARs in proton therapy
for breast cancer and to study the relationship of the LETd-weighted biological dose relative …

Quantification of biological range uncertainties in patients treated at the Krakow proton therapy centre

M Garbacz, J Gajewski, M Durante, K Kisielewicz… - Radiation …, 2022 - Springer
Background Variable relative biological effectiveness (vRBE) in proton therapy might
significantly modify the prediction of RBE-weighted dose delivered to a patient during proton …

Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors

OM Otterlei, DJ Indelicato, L Toussaint… - Acta …, 2021 - Taylor & Francis
Background Clinically, a constant value of 1.1 is used for the relative biological effectiveness
(RBE) of protons, whereas in vitro the RBE has been shown to vary depending on physical …

Response to:'Comments on" Temporal lobe sparing radiotherapy with photons or protons for cognitive function preservation in paediatric craniopharyngioma" by …

L Toussaint, DJ Indelicato, LP Muren, Z Li… - … Oncology: Journal of …, 2021 - europepmc.org
This is a comment on" Comments on" Temporal lobe sparing radiotherapy with photons or
protons for cognitive function preservation in paediatric craniopharyngioma" by Toussaint, et …

A Theoretical Review to Analyze the Response Between the Radiographic Film and the Living Tissue in Terms of Energy Absorption

D Bhagabati, R Bhattacharjee, B Nath… - Selected Progresses in …, 2021 - Springer
The concept of this theoretical work has been boosted by the fact that different medium
responds to ionizing radiation in different ways. In diagnostic radiology, patients are being …