Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

The safety of progestogens as a class has come under increased scrutiny after the
publication of data from the Women's Health Initiative trial, particularly with respect to breast …

In aquatic ecosystems, progesterone (P4) and synthetic progestins (gestagens) originate
from excretion by humans and livestock. Synthetic progestins are used for contraception and …

Synthetic progestins are used by millions of women as contraceptives and in hormone
replacement therapy (HRT), although their molecular mechanisms of action are not well …

Sex steroid hormones play important physiological roles in reproductive and
nonreproductive tissues, including immune cells. These hormones exert their functions by …

In this review we systematically summarize the effects of progesterone and synthetic
progestins on neurogenesis, synaptogenesis, myelination and six neurotransmitter systems …

Membrane progesterone receptors (mPRs) are novel G protein-coupled receptors belonging
to the progestin and adipoQ receptor family (PAQR) that mediate a variety of rapid cell …

Female sex is associated with improved outcome in experimental brain injury models, such
as traumatic brain injury, ischemic stroke, and intracerebral hemorrhage. This implies female …

In addition to the classic genomic mechanism of steroid action mediated by activation of
intracellular nuclear receptors, there is now extensive evidence that steroids also activate …

The major progestin in teleosts is not progesterone, as in tetrapods, but 17, 20β‐
dihydroxypregn‐4‐en‐3‐one (17, 20β‐P) or, in certain species, 17, 20β, 21‐trihydroxy …