Cellular communications play pivotal roles in multi-cellular species, but they do so also in
uni-cellular species. Moreover, cells communicate with each other not only within the same …

Proper regulation of ion balance across the intestinal epithelium is essential for
physiological functions, while ion imbalance causes intestinal disorders with dire health …

Connexins are membrane expressed proteins, which could assemble into hexamers to
transfer metabolites and secondary messengers. However, its roles in pancreatic cancer …

T-cell exhaustion (Tex) is considered to be a reason for immunotherapy resistance and poor
prognosis in lung adenocarcinoma. Therefore, we used weighted correlation network …

Gap junctional channels are specialized components of the cellular membrane that allow
the intercellular passage of small metabolites, ions, and second messengers to maintain …

Cataract is a common disease in the aging population. Gap junction has been considered a
central component in maintaining homeostasis for preventing cataract formation. Gap …

Necroptosis is an alternative form of programmed cell death that generally occurs under
apoptosis‐deficient conditions. Our previous work showed that connexin32 (Cx32) promotes …

Cells of vertebrate and invertebrate organisms express proteins specialized in membrane
channel–based cell–cell communication that are absent in unicellular organisms. We …

Objective The aim of this study was to investigate the regulatory mechanism of Pb regulates
gap junction intercellular communication to induced apoptosis in H9c2 cells. Methods H9c2 …

Aquaporins constitute a group of water channel proteins located in numerous cell types.
These are pore-forming transmembrane proteins, which mediate the specific passage of …