The volume-sensitive outwardly rectifying or volume-regulated anion channel, VSOR/VRAC,
which was discovered in 1988, is expressed in most vertebrate cell types and is essentially …

Vascular inflammation underlies the development of hypertension, and the mechanisms by
which it increases blood pressure remain the topic of intense investigation. Proinflammatory …

Volume-regulated anion channels (VRACs) participate in the cellular response to osmotic
swelling. These membrane proteins consist of heteromeric assemblies of LRRC8 subunits …

Volume-regulated anion channels (VRACs) are hexamers of LRRC8 proteins that are
crucial for cell volume regulation. N termini (NTs) of the obligatory LRRC8A subunit …

Volume‐regulated anion channels (VRACs) formed by leucin‐rich repeat containing 8
(LRRC8) proteins play a pivotal role in regulatory volume decrease by mediating the release …

Leucine-rich repeat-containing 8A (LRRC8A) is a key component of the volume-regulated
anion channel (VRAC) that influences essential homeostatic processes in various immune …

Members of the LRRC8 protein family form heteromeric ion and osmolyte channels with
roles in numerous physiological processes. As volume-regulated anion channels …

Volume-regulated anion channels (VRACs) and the acid-sensitive outwardly rectifying anion
channel (ASOR) mediate flux of chloride and small organic anions. Although known for a …

Chloride homeostasis is critical in the physiological functions of the central nervous system
(CNS). Its concentration is precisely regulated by multiple ion-transporting proteins such as …

Objective: In this study, we utilized bibliometric methods to assess the worldwide scientific
output and identify hotspots related to the research on the volume-regulated anion channel …