Heterogeneity of type 2 innate lymphoid cells
H Spits, J Mjösberg - Nature Reviews Immunology, 2022 - nature.com
More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …
members of a family of innate immune cells consisting of five subsets that form a first line of …
Emerging concepts in intestinal immune control of obesity-related metabolic disease
The intestinal immune system is an important modulator of glucose homeostasis and obesity-
associated insulin resistance. Dietary factors, the intestinal microbiota and their metabolites …
associated insulin resistance. Dietary factors, the intestinal microbiota and their metabolites …
[HTML][HTML] Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response
The role of innate immune cells in allergen immunotherapy that confers immune tolerance to
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …
Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity
CSN Klose, D Artis - Cell research, 2020 - nature.com
The multifaceted organization of the immune system involves not only patrolling
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …
Spatial heterogeneity of bacterial colonization across different gut segments following inter-species microbiota transplantation
Background The microbiota presents a compartmentalized distribution across different gut
segments. Hence, the exogenous microbiota from a particular gut segment might only …
segments. Hence, the exogenous microbiota from a particular gut segment might only …
[HTML][HTML] Dietary fiber metabolites regulate innate lymphoid cell responses
Innate lymphoid cells (ILCs) rapidly undergo expansion in population size and functional
maturation in response to cytokines that signal infection, tissue damage, or changes in …
maturation in response to cytokines that signal infection, tissue damage, or changes in …
Innate lymphoid cells in autoimmune diseases
AS Clottu, M Humbel, N Fluder… - Frontiers in …, 2022 - frontiersin.org
Innate lymphoid cells (ILC) are a heterogeneous group of immune cells characterized by
lymphoid morphology and cytokine profile similar to T cells but which do not express clonally …
lymphoid morphology and cytokine profile similar to T cells but which do not express clonally …
Cross-talk between ILC2 and Gata3high Tregs locally constrains adaptive type 2 immunity
Regulatory T cells (Tregs) control adaptive immunity and restrain type 2 inflammation in
allergic disease. Interleukin-33 promotes the expansion of tissue-resident Tregs and group 2 …
allergic disease. Interleukin-33 promotes the expansion of tissue-resident Tregs and group 2 …
Mechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking
S Gu, Y Xue, Y Gao, S Shen, Y Zhang, K Chen, S Xue… - Scientific reports, 2020 - nature.com
Oral administration of indigo naturalis (IN) can induce remission in ulcerative colitis (UC);
however, the underlying mechanism remains unknown. The main active components and …
however, the underlying mechanism remains unknown. The main active components and …
Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response
AK Kammala, A Mosebarger, E Radnaa… - Frontiers in …, 2023 - frontiersin.org
Background Fetal inflammatory response mediated by the influx of immune cells and
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …