Microglia are dispensable for experience-dependent refinement of mouse visual circuitry
TC Brown, EC Crouse, CA Attaway, DK Oakes… - Nature …, 2024 - nature.com
To test the hypothesized crucial role of microglia in the developmental refinement of neural
circuitry, we depleted microglia from mice of both sexes with PLX5622 and examined the …
circuitry, we depleted microglia from mice of both sexes with PLX5622 and examined the …
Thalamocortical circuits and functional architecture
The thalamocortical pathway is the main route of communication between the eye and the
cerebral cortex. During embryonic development, thalamocortical afferents travel to L4 and …
cerebral cortex. During embryonic development, thalamocortical afferents travel to L4 and …
[HTML][HTML] Punctuated evolution of visual cortical circuits? Evidence from the large rodent Dasyprocta leporina, and the tiny primate Microcebus murinus
KE Schmidt, F Wolf - Current opinion in neurobiology, 2021 - Elsevier
Recent reports of the lack of periodic orientation columns in a very large rodent species, the
red-rumped agouti, and the existence of incompressible hypercolumns in the lineage of …
red-rumped agouti, and the existence of incompressible hypercolumns in the lineage of …
Functional connectomics reveals general wiring rule in mouse visual cortex
Understanding the relationship between circuit connectivity and function is crucial for
uncovering how the brain implements computation. In the mouse primary visual cortex (V1) …
uncovering how the brain implements computation. In the mouse primary visual cortex (V1) …
[HTML][HTML] Vision changes the cellular composition of binocular circuitry during the critical period
High acuity stereopsis emerges during an early postnatal critical period when binocular
neurons in the primary visual cortex sharpen their receptive field tuning properties. We find …
neurons in the primary visual cortex sharpen their receptive field tuning properties. We find …
Natural image and receptive field statistics predict saccade sizes
Humans and other primates sample the visual environment using saccadic eye movements
that shift a high-resolution fovea toward regions of interest to create a clear perception of a …
that shift a high-resolution fovea toward regions of interest to create a clear perception of a …
Widespread and multifaceted binocular integration in the mouse primary visual cortex
The brain combines two-dimensional images received from the two eyes to form a percept of
three-dimensional surroundings. This process of binocular integration in the primary visual …
three-dimensional surroundings. This process of binocular integration in the primary visual …
Long-term monocular deprivation during juvenile critical period disrupts binocular integration in mouse visual thalamus
Study of the neural deficits caused by mismatched binocular vision in early childhood has
predominantly focused on circuits in the primary visual cortex (V1). Recent evidence has …
predominantly focused on circuits in the primary visual cortex (V1). Recent evidence has …
The development of receptive field tuning properties in mouse binocular primary visual cortex
The mouse primary visual cortex is a model system for understanding the relationship
between cortical structure, function, and behavior (;;;;). Binocular neurons in V1 are the …
between cortical structure, function, and behavior (;;;;). Binocular neurons in V1 are the …
[HTML][HTML] But still it moves: static image statistics underlie how we see motion
R Rideaux, AE Welchman - Journal of Neuroscience, 2020 - Soc Neuroscience
Seeing movement promotes survival. It results from an uncertain interplay between evolution
and experience, making it hard to isolate the drivers of computational architectures found in …
and experience, making it hard to isolate the drivers of computational architectures found in …