Invariant natural killer T cells (iNKT cells) are an innate-like T cell subset that expresses an
invariant T cell receptor (TCR) α-chain and recognizes lipids presented on CD1d. They …

Invariant natural killer T (iNKT) cells exist in a'poised effector'state, which enables them to
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …

Secondary bacterial infections often complicate viral respiratory infections. We hypothesize
that perturbation of the gut microbiota during influenza A virus (IAV) infection might favor …

Disclosures: S. Ehrmann reported personal fees from Aerogen, grants from Fisher & Paykel,
grants from Hamilton Medical, and personal fees from La Diffusion Technique Française …

Mucosal-associated invariant T (MAIT) cells are abundant in humans and recognize
bacterial ligands. Here, we demonstrate that MAIT cells are also activated during human …

Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but
emergence of viral variants that are antigenically distinct from the vaccine strains are of …

Mucosal associated invariant T (MAIT) cells are evolutionarily-conserved, innate-like
lymphocytes which are abundant in human lungs and can contribute to protection against …

Influenza viruses cause annual outbreaks of respiratory tract infection with attack rates of 5–
10%. This means that humans are infected repeatedly with intervals of, on average, 10–20 …

Over the past 15 years, investigators have shown that T lymphocytes can recognize not only
peptides in the context of MHC class I and class II molecules but also foreign and self-lipids …

Evidence has increasingly shown that the lungs are a major site of immune regulation. A
robust and highly regulated immune response in the lung protects the host from pathogen …