Perspectives on the Drosophila melanogaster Model for Advances in Toxicological Science

MD Rand, JM Tennessen, TFC Mackay… - Current …, 2023 - Wiley Online Library
The use of Drosophila melanogaster for studies of toxicology has grown considerably in the
last decade. The Drosophila model has long been appreciated as a versatile and powerful …

Drosophila melanogaster as a Versatile Model Organism in Food and Nutrition Research

S Staats, K Lüersen, AE Wagner… - Journal of agricultural …, 2018 - ACS Publications
Drosophila melanogaster has been widely used in the biological sciences as a model
organism. Drosophila has a relatively short life span of 60–80 days, which makes it attractive …

dFRAME: A Video Recording-Based Analytical Method for Studying Feeding Rhythm in Drosophila

M Niu, X Zhang, W Li, J Wang, Y Li - Frontiers in Genetics, 2021 - frontiersin.org
Animals, from insects to humans, exhibit obvious diurnal rhythmicity of feeding behavior.
Serving as a genetic animal model, Drosophila has been reported to display feeding …

Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency

L Granat, DY Knorr, DC Ranson, EL Hamer… - PLoS …, 2023 - journals.plos.org
Mutations in subunits of the mitochondrial NADH dehydrogenase cause mitochondrial
complex I deficiency, a group of severe neurological diseases that can result in death in …

A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster

AN Belovich, JI Aguilar, SJ Mabry, MH Cheng… - Molecular …, 2021 - nature.com
Reward modulates the saliency of a specific drug exposure and is essential for the transition
to addiction. Numerous human PET–fMRI studies establish a link between midbrain …

The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila

TT Dang, YH Huang, S Ott, PJ Harvey… - Journal of Biological …, 2022 - ASBMB
Cyclotides and acyclic versions of cyclotides (acyclotides) are peptides involved in plant
defense. These peptides contain a cystine knot motif formed by three interlocked disulfide …

Fat storage in Drosophila suzukii is influenced by different dietary sugars in relation to their palatability

M Biolchini, E Murru, G Anfora, F Loy, S Banni… - PloS one, 2017 - journals.plos.org
The peripheral sensitivity and palatability of different carbohydrates was evaluated and their
nutritional value assessed in adult females of D. suzukii by means of an …

Effects of Drosophila melanogaster regular exercise and apolipoprotein B knockdown on abnormal heart rhythm induced by a high-fat diet

M Ding, QF Li, G Yin, JL Liu, XY Jan, T Huang, AC Li… - PLoS …, 2022 - journals.plos.org
Abnormal heart rhythm is a common cardiac dysfunction in obese patients, and its
pathogenesis is related to systemic lipid accumulation. The cardiomyocyte-derived apoLpp …

Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors

TL Fulton, JN Johnstone, JJ Tan… - Open …, 2024 - royalsocietypublishing.org
Nutrition and resilience are linked, though it is not yet clear how diet confers stress
resistance or the breadth of stressors that it can protect against. We have previously shown …

EasyFlyTracker: A Simple Video Tracking Python Package for Analyzing Adult Drosophila Locomotor and Sleep Activity to Facilitate Revealing the Effect of …

S Qu, Q Zhu, H Zhou, Y Gao, Y Wei, Y Ma… - Frontiers in Behavioral …, 2022 - frontiersin.org
The mechanism of psychiatric drugs (stimulant and non-stimulant) is still unclear. Precision
medication of psychiatric disorders faces challenges in pharmacogenetics and …