Aurora kinases are serine/threonine kinases essential for the onset and progression of
mitosis. Aurora members share a similar protein structure and kinase activity, but exhibit …

Temporally and spatially controlled activation of the Aurora A kinase (AURKA) regulates
centrosome maturation, entry into mitosis, formation and function of the bipolar spindle, and …

Mitosis is controlled by reversible protein phosphorylation involving specific kinases and
phosphatases. A handful of major mitotic protein kinases, such as the cyclin B–CDK1 …

When the nucleolus disassembles during open mitosis, many nucleolar proteins and RNAs
associate with chromosomes, establishing a perichromosomal compartment coating the …

The centrosome acts as the major microtubule-organizing center (MTOC) for cytoskeleton
maintenance in interphase and mitotic spindle assembly in vertebrate cells. It duplicates …

The unique ability of centrosomes to nucleate and organize microtubules makes them
unrivaled conductors of important interphase processes, such as intracellular payload traffic …

Aurora kinases control multiple events during cell cycle progression and are essential for
mitotic and meiotic bipolar spindle assembly and function. There are three Aurora kinases in …

The Aurora kinase A (AURKA) is involved in different aspects of mitotic control, from mitotic
entry to cytokinesis. Consistent with its pleiotropic roles, several AURKA interactors are able …

The essential mitotic kinase Aurora A (AURKA) is controlled during cell cycle progression
via two distinct mechanisms. Following activation loop autophosphorylation early in mitosis …

Accurate chromosome segregation requires the perfect spatiotemporal rearrangement of the
cellular cytoskeleton. Isolated more than two decades ago from Drosophila, Aurora A is a …