Genome-wide association studies in diverse populations
NA Rosenberg, L Huang, EM Jewett… - Nature Reviews …, 2010 - nature.com
Genome-wide association (GWA) studies have identified a large number of SNPs
associated with disease phenotypes. As most GWA studies have been performed in …
associated with disease phenotypes. As most GWA studies have been performed in …
Interethnic admixture and the evolution of Latin American populations
FM Salzano, M Sans - Genetics and molecular biology, 2014 - SciELO Brasil
A general introduction to the origins and history of Latin American populations is followed by
a systematic review of the data from molecular autosomal assessments of the …
a systematic review of the data from molecular autosomal assessments of the …
Principal Component Analyses (PCA)-based findings in population genetic studies are highly biased and must be reevaluated
E Elhaik - Scientific Reports, 2022 - nature.com
Abstract Principal Component Analysis (PCA) is a multivariate analysis that reduces the
complexity of datasets while preserving data covariance. The outcome can be visualized on …
complexity of datasets while preserving data covariance. The outcome can be visualized on …
[HTML][HTML] The genetic ancestry of african americans, latinos, and european Americans across the United States
K Bryc, EY Durand, JM Macpherson, D Reich… - The American Journal of …, 2015 - cell.com
Over the past 500 years, North America has been the site of ongoing mixing of Native
Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave …
Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave …
The genetics of Mexico recapitulates Native American substructure and affects biomedical traits
Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-
wide variation from this region remain largely uncharacterized. We studied genomic …
wide variation from this region remain largely uncharacterized. We studied genomic …
Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals
A Ruiz-Linares, K Adhikari, V Acuña-Alonzo… - PLoS …, 2014 - journals.plos.org
The current genetic makeup of Latin America has been shaped by a history of extensive
admixture between Africans, Europeans and Native Americans, a process taking place …
admixture between Africans, Europeans and Native Americans, a process taking place …
Genome-wide patterns of population structure and admixture among Hispanic/Latino populations
K Bryc, C Velez, T Karafet… - Proceedings of the …, 2010 - National Acad Sciences
Hispanic/Latino populations possess a complex genetic structure that reflects recent
admixture among and potentially ancient substructure within Native American, European …
admixture among and potentially ancient substructure within Native American, European …
Exploring patterns enriched in a dataset with contrastive principal component analysis
Visualization and exploration of high-dimensional data is a ubiquitous challenge across
disciplines. Widely used techniques such as principal component analysis (PCA) aim to …
disciplines. Widely used techniques such as principal component analysis (PCA) aim to …
[图书][B] Holy science: The biopolitics of Hindu nationalism
B Subramaniam - 2019 - books.google.com
Behind the euphoric narrative of India as an emerging world power lies a complex and
evolving relationship between science and religion. Evoking the rich mythology of …
evolving relationship between science and religion. Evoking the rich mythology of …
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas
Most individuals throughout the Americas are admixed descendants of Native American,
European, and African ancestors. Complex historical factors have resulted in varying …
European, and African ancestors. Complex historical factors have resulted in varying …