The hallmarks of cancer are also the hallmarks of wound healing

L MacCarthy-Morrogh, P Martin - Science Signaling, 2020 - science.org
The Hanahan and Weinberg “hallmarks of cancer” papers provide a useful structure for
considering the various mechanisms driving cancer progression, and the same might be …

Activin-A in the regulation of immunity in health and disease

I Morianos, G Papadopoulou, M Semitekolou… - Journal of …, 2019 - Elsevier
The TGF-β superfamily of cytokines plays pivotal roles in the regulation of immune
responses protecting against or contributing to diseases, such as, allergy, autoimmunity and …

Macrophages are necessary for epimorphic regeneration in African spiny mice

J Simkin, TR Gawriluk, JC Gensel, AW Seifert - elife, 2017 - elifesciences.org
How the immune system affects tissue regeneration is not well understood. In this study, we
used an emerging mammalian model of epimorphic regeneration, the African spiny mouse …

Research trends in pharmacological modulation of tumor‐associated macrophages

N Wang, S Wang, X Wang, Y Zheng… - Clinical and …, 2021 - Wiley Online Library
As one of the most abundant immune cell populations in the tumor microenvironment (TME),
tumor‐associated macrophages (TAMs) play important roles in multiple solid malignancies …

Production and Characterization of Exopolysaccharide From Newly Isolated Marine Probiotic Lactiplantibacillus plantarum EI6 With in vitro Wound Healing Activity

EH Zaghloul, MIA Ibrahim - Frontiers in Microbiology, 2022 - frontiersin.org
Because of its safety, biological activities, and unique properties, exopolysaccharide (EPS)
from lactic acid bacteria (LAB) has been developed as a potential biopolymer. A few studies …

IL-17A modulates peritoneal macrophage recruitment and M2 polarization in endometriosis

JE Miller, SH Ahn, RM Marks, SP Monsanto… - Frontiers in …, 2020 - frontiersin.org
Endometriosis is a debilitating gynecological disease characterized by the extrauterine
presence of endometrial-like tissues located on the peritoneal membrane and organs of the …

Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis

T Muliaditan, J Caron, M Okesola, JW Opzoomer… - Nature …, 2018 - nature.com
Tumour-associated macrophages (TAMs) play an important role in tumour progression,
which is facilitated by their ability to respond to environmental cues. Here we report, using …

Development, characterization and use of liposomes as amphipathic transporters of bioactive compounds for melanoma treatment and reduction of skin inflammation …

ED Castañeda-Reyes, MJ Perea-Flores… - International journal …, 2020 - Taylor & Francis
The skin is the largest organ in the human body, providing a barrier to the external
environment. It is composed of three layers: epidermis, dermis and hypodermis. The most …

Nanoparticle-based drug delivery systems to enhance cancer immunotherapy in solid tumors

J Zhang, S Wang, D Zhang, X He, X Wang… - Frontiers in …, 2023 - frontiersin.org
Immunotherapy has developed rapidly in solid tumors, especially in the areas of blocking
inhibitory immune checkpoints and adoptive T-cell transfer for immune regulation. Many …

Pro-tumorigenic functions of macrophages at the primary, invasive and metastatic tumor site

E Nasrollahzadeh, S Razi, M Keshavarz-Fathi… - Cancer Immunology …, 2020 - Springer
The tumor microenvironment (TME) not only facilitates cancer progression from the early
formation to distant metastasis, but also it differs itself from time to time alongside the tumor …