Altered Functional connectivity of basal ganglia in mild cognitive impairment and Alzheimer's disease

Y Xiong, C Ye, Y Chen, X Zhong, H Chen, R Sun… - Brain Sciences, 2022 - mdpi.com
(1) Background: Alzheimer's disease (AD), an age-progressive neurodegenerative disease
that affects cognitive function, causes changes in the functional connectivity of the default …

Microstructural brain assessment in late-life depression and apathy using diffusion MRI multi-compartments models and tractometry

R Hédouin, JC Roy, T Desmidt, G Robert… - Scientific Reports, 2024 - nature.com
Late-life depression (LLD) is both common and disabling and doubles the risk of dementia
onset. Apathy might constitute an additional risk of cognitive decline but clear understanding …

Microstructural brain assessment in late-life depression and apathy using diffusion MRI multi-compartments models associated with tractometry

R Hedouin, JC Roy, T Desmidt, G Robert, J Coloigner - 2024 - researchsquare.com
Late-life depression is a common disorder in the elderly, difficult to treat, where apathy
contributes to a poor prognosis. Despite its severity and frequency, the pathophysiology of …