The mechanisms underlying innate immune memory have been extensively explored in the
last decades but are in fact largely unknown. Although the specificity of adaptive immune …

The innate immune system is able to build memory-like features in response to certain
infections or vaccines, resulting in enhanced responsiveness upon (re) challenge with the …

Background Trials done in infants with low birthweight in west Africa suggest that BCG
vaccination reduces all-cause mortality in the neonatal period, probably because of …

Natural Killer (NK) cells are innate immune responders critical for viral clearance and
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …

The textbook view of vaccination is that it functions to induce immune memory of the specific
pathogen components of the vaccine, leading to a quantitatively and qualitatively better …

During acute infectious and inflammatory conditions, a large number of neutrophils are in
high demand as they are consumed in peripheral organs. The hematopoietic system rapidly …

Introduction Recent evidence suggests that influenza vaccination may offer protection
against COVID-19 severity. Our aim was to quantify the association between influenza …

BCG turns 100 this year and while it might not be the perfect vaccine, it has certainly
contributed significantly towards eradication and prevention of spread of tuberculosis (TB) …

In addition to providing partial protection against pediatric tuberculosis, vaccination with
bacille Calmette-Guérin (BCG) has been reported to confer nonspecific resistance to …

Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …