Porcine reproductive and respiratory syndrome virus (PRRSV): pathogenesis and interaction with the immune system

JK Lunney, Y Fang, A Ladinig, N Chen… - Annual review of …, 2016 - annualreviews.org
This review addresses important issues of porcine reproductive and respiratory syndrome
virus (PRRSV) infection, immunity, pathogenesis, and control. Worldwide, PRRS is the most …

[HTML][HTML] Arterivirus molecular biology and pathogenesis

EJ Snijder, M Kikkert, Y Fang - Journal of General …, 2013 - microbiologyresearch.org
Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause
persistent or asymptomatic infections, but also acute disease associated with a respiratory …

Function of HNRNPC in breast cancer cells by controlling the dsRNA‐induced interferon response

Y Wu, W Zhao, Y Liu, X Tan, X Li, Q Zou, Z Xiao… - The EMBO …, 2018 - embopress.org
Elevated expression of RNA binding protein HNRNPC has been reported in cancer cells,
while the essentialness and functions of HNRNPC in tumors were not clear. We showed that …

Innate and adaptive immunity against porcine reproductive and respiratory syndrome virus

CL Loving, FA Osorio, MP Murtaugh… - Veterinary immunology …, 2015 - Elsevier
Many highly effective vaccines have been produced against viruses whose virulent infection
elicits strong and durable protective immunity. In these cases, characterization of immune …

[HTML][HTML] Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1

Q Zhang, K Shi, D Yoo - Virology, 2016 - Elsevier
Type I interferons (IFN-α/β) are the major components of the innate immune response of
hosts, and in turn many viruses have evolved to modulate the host response during …

[HTML][HTML] Key gaps in the knowledge of the porcine respiratory reproductive syndrome virus (PRRSV)

S Montaner-Tarbes, HA Del Portillo… - Frontiers in veterinary …, 2019 - frontiersin.org
The porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
important swine diseases in the world. It is causing an enormous economic burden due to …

Pathogenesis and control of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus

J Han, L Zhou, X Ge, X Guo, H Yang - Veterinary microbiology, 2017 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has remained a major threat
to the worldwide swine industry ever since its first discovery in the early 1990s. Under the …

[HTML][HTML] Porcine reproductive and respiratory syndrome modified live virus vaccine: a “leaky” vaccine with debatable efficacy and safety

L Zhou, X Ge, H Yang - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome (PRRS) caused by the PRRS virus (PRRSV)
is one of the most economically important diseases, that has significantly impacted the …

Molecular and cellular mechanisms for PRRSV pathogenesis and host response to infection

TQ An, JN Li, CM Su, D Yoo - Virus research, 2020 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous
amounts of economic losses to the swine industry for more than three decades, but its …

[HTML][HTML] Nsp9 and Nsp10 contribute to the fatal virulence of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China

Y Li, L Zhou, J Zhang, X Ge, R Zhou, H Zheng… - PLoS …, 2014 - journals.plos.org
Atypical porcine reproductive and respiratory syndrome (PRRS), which is caused by the
Chinese highly pathogenic PRRS virus (HP-PRRSV), has resulted in large economic loss to …