Drug repurposing is promoted as a cost-and time-effective mechanism for providing new
medicines. Often, however, there is insufficient consideration by academic researchers of …

Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …

Airway epithelium forms a physical barrier that protects the lung from the entrance of inhaled
allergens, irritants, or microorganisms. This epithelial structure is maintained by tight …

Simple Summary Breast cancer is a major public health problem with a large impact on the
life of patients and their families. It is a highly curable disease when detected early, and an …

The use of already-approved drugs to treat new or alternative diseases has proved to be
beneficial in medicine, because it reduces both drug development costs and timelines. Most …

Slow-cycling/dormant cancer cells (SCCs) have pivotal roles in driving cancer relapse and
drug resistance. A mechanistic explanation for cancer cell dormancy and therapeutic …

Cancer is one of the leading causes of death worldwide, and the development of resistance
to chemotherapy drugs is a major challenge in treating malignancies. In recent years …

Drug repurposing is a major field of value-added medicine. It involves investigating and
evaluating existing drugs for new therapeutic purposes that address unmet healthcare …

The chemotherapy resistance of esophageal adenocarcinomas (EACs) is underpinned by
cancer cell extrinsic mechanisms of the tumor microenvironment (TME). We demonstrate …