The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment

A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …

COVID-19, oxidative stress, and neuroinflammation in the depression route

MED Mingoti, AG Bertollo, JLB Simões… - Journal of Molecular …, 2022 - Springer
COVID-19 is associated with oxidative stress, peripheral hyper inflammation, and
neuroinflammation, especially in individuals with a more severe form of the disease. Some …

Relationship of oxidative stress as a link between diabetes mellitus and major depressive disorder

GZ Réus, AS Carlessi, RH Silva… - Oxidative medicine …, 2019 - Wiley Online Library
Both conditions, major depressive disorder (MDD) and diabetes mellitus (DM) are chronic
and disabling diseases that affect a very significant percentage of the world's population …

Metabolic signature in nucleus accumbens for anti-depressant-like effects of acetyl-L-carnitine

A Cherix, T Larrieu, J Grosse, J Rodrigues, B McEwen… - Elife, 2020 - elifesciences.org
Emerging evidence suggests that hierarchical status provides vulnerability to develop stress-
induced depression. Energy metabolic changes in the nucleus accumbens (NAc) were …

Oxidation-reduction mechanisms in psychiatric disorders: A novel target for pharmacological intervention

AC Rossetti, MS Paladini, MA Riva, R Molteni - Pharmacology & …, 2020 - Elsevier
While neurotransmitter dysfunction represents a key component in mental illnesses, there is
now a wide agreement for a central pathophysiological hub that includes hormones …

Microglial Inflammatory Responses to SARS‐CoV‐2 Infection: A Comprehensive Review

R Dey, B Bishayi - Cellular and Molecular Neurobiology, 2024 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is primarily a respiratory disease causing a
worldwide pandemic in the year of 2019. SARS‐CoV‐2 is an enveloped, positive-stranded …

[HTML][HTML] Neuroprotective potential of solanesol in intracerebroventricular propionic acid induced experimental model of autism: Insights from behavioral and …

R Sharma, S Rahi, S Mehan - Toxicology reports, 2019 - Elsevier
Autism is the category used within the newest edition of the diagnostic and statistical manual
of neurodevelopmental disorders. Autism is a spectrum of disorder where a variety of …

Quetiapine moderates doxorubicin-induced cognitive deficits: Influence of oxidative stress, neuroinflammation, and cellular apoptosis

V Mani, BS Alshammeri - International Journal of Molecular Sciences, 2023 - mdpi.com
Chemotherapy is considered a major choice in cancer treatment. Unfortunately, several
cognitive deficiencies and psychiatric complications have been reported in patients with …

Putative neuroprotective pharmacotherapies to target the staged progression of mental illness

OD Robertson, NG Coronado, R Sethi… - Early intervention in …, 2019 - Wiley Online Library
Aim Neuropsychiatric disorders including depression, bipolar and schizophrenia frequently
exhibit a neuroprogressive course from prodrome to chronicity. There are a range of agents …

ω-3 and folic acid act against depressive-like behavior and oxidative damage in the brain of rats subjected to early-or late-life stress

GZ Reus, AL Maciel, HM Abelaira, AB de Moura… - Nutrition, 2018 - Elsevier
Objectives To investigate the antidepressant and antioxidant effects of omega-3, folic acid
and n-acetylcysteine (NAC) in rats which were subjected to early or late life stress. Methods …