Maternal folic acid supplementation mediates offspring health via DNA methylation

HY Liu, SM Liu, YZ Zhang - Reproductive Sciences, 2020 - Springer
The clinical significance of periconceptional folic acid supplementation (FAS) in the
prevention of neonatal neural tube defects (NTDs) has been recognized for decades …

Perinatal selective serotonin reuptake inhibitor (SSRI) and other antidepressant exposure effects on anxiety and depressive behaviors in offspring: a review of findings …

SM Hutchison, LC Mâsse, JL Pawluski… - Reproductive …, 2021 - Elsevier
The developmental impact of selective serotonin reuptake inhibitor (SSRI) and other
antidepressant treatments during gestation and postpartum on anxiety and depression …

General psychopathology, internalising and externalising in children and functional outcomes in late adolescence

H Sallis, E Szekely, A Neumann… - Journal of Child …, 2019 - Wiley Online Library
Background Internalising and externalising problems commonly co‐occur in childhood. Yet,
few developmental models describing the structure of child psychopathology appropriately …

Corticolimbic DCC gene co-expression networks as predictors of impulsivity in children

JM Restrepo-Lozano, I Pokhvisneva, Z Wang… - Molecular …, 2022 - nature.com
Inhibitory control deficits are prevalent in multiple neuropsychiatric conditions. The
communication-as well as the connectivity-between corticolimbic regions of the brain are …

[HTML][HTML] Maternal prenatal mood, pregnancy-specific worries, and early child psychopathology: findings from the DREAM BIG consortium

E Szekely, A Neumann, H Sallis… - Journal of the American …, 2021 - Elsevier
Objective Few studies have attempted to identify how distinct dimensions of maternal
prenatal affective symptoms relate to offspring psychopathology. We defined latent …

Perinatal selective serotonin reuptake inhibitor medication (SSRI) effects on social behaviors, neurodevelopment and the epigenome

M Gemmel, E Bögi, C Ragan, M Hazlett… - Neuroscience & …, 2018 - Elsevier
Recent research has linked early life exposure to selective serotonin reuptake inhibitor
medications (SSRIs) to modifications of social behaviors in children. Serotonin is a key …

Cumulative prenatal exposure to adversity reveals associations with a broad range of neurodevelopmental outcomes that are moderated by a novel, biologically …

PP Silveira, I Pokhvisneva, C Parent, S Cai… - Development and …, 2017 - cambridge.org
While many studies focus on the association between early life adversity and the later risk
for psychopathology, few simultaneously explore diverse forms of environmental adversity …

Maternal symptoms of depression and sensitivity mediate the relation between maternal history of early adversity and her child temperament: the inheritance of …

AA Bouvette-Turcot, AS Fleming… - Development and …, 2020 - cambridge.org
We examined maternal depression and maternal sensitivity as mediators of the association
between maternal childhood adversity and her child's temperament in 239 mother–child …

A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions

SAH Dass, K McCracken, I Pokhvisneva, LM Chen… - …, 2019 - thelancet.com
Background Activation of brain insulin receptors modulates reward sensitivity, inhibitory
control and memory. Variations in the functioning of this mechanism likely associate with …

Prenatal depression and 5‐HTTLPR interact to predict dysregulation from 3 to 36 months–A differential susceptibility model

V Babineau, CG Green… - Journal of Child …, 2015 - Wiley Online Library
Background Childhood dysregulation, which reflects deficits in the capacity to regulate or
control one's thoughts, emotions and behaviours, is associated with psychopathology …