Surface‐acoustic‐wave (SAW) induced mixing enhances the detection of viruses: application to measles sensing in whole human saliva with a SAW lab‐on‐a‐chip

M Agostini, F Lunardelli, M Gagliardi… - Advanced Functional …, 2022 - Wiley Online Library
Measles is one of the most infectious airborne viruses worldwide. With a basic reproduction
rate between 12–18, this virus is six times more infectious than the SARS‐CoV‐2 Alpha …

Palmitoylethanolamide (PEA) inhibits SARS-CoV-2 entry by interacting with S protein and ACE-2 receptor

R Fonnesu, VBSC Thunuguntla, GK Veeramachaneni… - Viruses, 2022 - mdpi.com
Lipids play a crucial role in the entry and egress of viruses, regardless of whether they are
naked or enveloped. Recent evidence shows that lipid involvement in viral infection goes …

CRISPR/Cas9 ablation of integrated HIV-1 accumulates proviral DNA circles with reformed long terminal repeats

M Lai, E Maori, P Quaranta, G Matteoli, F Maggi… - Journal of …, 2021 - Am Soc Microbiol
Gene editing may be used to excise the human immunodeficiency virus type 1 (HIV-1)
provirus from the host cell genome, possibly eradicating the infection. Here, using cells …

Zika virus induces FOXG1 nuclear displacement and downregulation in human neural progenitors

G Lottini, M Baggiani, G Chesi, B D'Orsi, P Quaranta… - Stem Cell Reports, 2022 - cell.com
Congenital alterations in the levels of the transcription factor Forkhead box g1 (FOXG1)
coding gene trigger" FOXG1 syndrome," a spectrum that recapitulates birth defects found in …

[HTML][HTML] Inhibiting immunoregulatory amidase NAAA blocks ZIKV maturation in Human Neural Stem Cells

M Lai, V La Rocca, E Iacono, C Filipponi, A De Carli… - Antiviral Research, 2023 - Elsevier
Recent evidence suggests that lipids play a crucial role in viral infections beyond their
traditional functions of supplying envelope and energy, and creating protected niches for …

[HTML][HTML] Broad-spectrum virucidal activity of a hydroalcoholic extract of grape pomace

E Iacono, C Di Marzo, M Di Stasi, E Cioni… - Bioresource Technology …, 2024 - Elsevier
Grape pomace is a by-product of winemaking often disposed of before full exploitation.
Indeed, this natural product holds great potential for sustainable utilization. In this study …

Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs)

F Riu, R Ibba, S Zoroddu, S Sestito, M Lai… - Journal of Enzyme …, 2022 - Taylor & Francis
Introduction: Colchicine-binding site inhibitors are some of the most interesting ligands
belonging to the wider family of microtubule-destabilising agents. Results: A novel series of …

Gene silencing of endothelial von Willebrand factor reduces the susceptibility of human endothelial cells to SARS‐CoV‐2 infection

G Furini, A De Carli, R Fonnesu, PG Spezia… - The FEBS …, 2023 - Wiley Online Library
Mechanisms underlying vascular endothelial susceptibility to infection by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are not fully understood. Emerging …

[HTML][HTML] Enhancing antimicrobial and antiviral properties of Cynara scolymus L. waste through enzymatic pretreatment and lactic fermentation

E Cioni, M Di Stasi, E Iacono, M Lai, P Quaranta… - Food Bioscience, 2024 - Elsevier
This study explores the potential of Cynara scolymus L.(artichoke) waste as bioactive
compounds resource with antimicrobial and antiviral properties. Three extracts were …

Comparative genomic analysis of Mycoplasma related to cell culture for infB gene-based loop-mediated isothermal amplification

B Luna-Callejas, L Oropeza-Ramos… - World Journal of …, 2023 - Springer
Mycoplasma contamination in cell culture affects the properties of cell lines. Gold standard
detection by microbiological culture takes days and requires specialists. The polymerase …