TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease
R Sartori, P Gregorevic, M Sandri - Trends in Endocrinology & Metabolism, 2014 - cell.com
The transforming growth factor beta (TGFβ) superfamily comprises a large number of
secreted proteins that regulate various fundamental biological processes underlying …
secreted proteins that regulate various fundamental biological processes underlying …
Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review
Q Zhang, Y Pan, J Ji, Y Xu, Q Zhang, L Qin - Cell death discovery, 2021 - nature.com
Abstract WNT family member 4 (WNT4), which belongs to the conserved WNT protein family,
plays an important role in the development and differentiation of many cell types during the …
plays an important role in the development and differentiation of many cell types during the …
Foxf1 knockdown promotes BMSC osteogenesis in part by activating the Wnt/β-catenin signalling pathway and prevents ovariectomy-induced bone loss
Background Forkhead box protein f1 (Foxf1) is associated with cell differentiation, and may
be a key player in bone homoeostasis. However, the effect of Foxf1 on osteogenesis of bone …
be a key player in bone homoeostasis. However, the effect of Foxf1 on osteogenesis of bone …
Cellular Feimin enhances exercise performance by suppressing muscle thermogenesis
Exercise can rapidly increase core body temperature, and research has indicated that
elevated internal body temperature can independently contribute to fatigue during physical …
elevated internal body temperature can independently contribute to fatigue during physical …
Muscle cell‐derived cytokines in skeletal muscle regeneration
Regeneration of the mammalian adult skeletal muscle is a well‐orchestrated process
regulated by multiple proteins and signalling pathways. Cytokines constitute a major class of …
regulated by multiple proteins and signalling pathways. Cytokines constitute a major class of …
Coactivation of endogenous Wnt10b and Foxc2 by CRISPR activation enhances BMSC osteogenesis and promotes calvarial bone regeneration
CRISPR activation (CRISPRa) is a burgeoning technology for programmable gene
activation, but its potential for tissue regeneration has yet to be fully explored. Bone marrow …
activation, but its potential for tissue regeneration has yet to be fully explored. Bone marrow …
Aging, obese-insulin resistance, and bone remodeling
N Imerb, C Thonusin, N Chattipakorn… - Mechanisms of Ageing …, 2020 - Elsevier
Aging, obesity, and insulin resistance are known to cause the impairment of bone regulation,
resulting in an imbalance in bone homeostasis and pathological bone. The natural …
resulting in an imbalance in bone homeostasis and pathological bone. The natural …
Regulation of Wnt signaling by FOX transcription factors in cancer
S Koch - Cancers, 2021 - mdpi.com
Simple Summary Cancer is caused by a breakdown of cell-to-cell communication, which
results in the unrestricted expansion of cells within a tissue. In many cases, tumor growth is …
results in the unrestricted expansion of cells within a tissue. In many cases, tumor growth is …
WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines
Background Invasive lobular carcinoma (ILC) of the breast typically presents with clinical
biomarkers consistent with a favorable response to endocrine therapies, and over 90% of …
biomarkers consistent with a favorable response to endocrine therapies, and over 90% of …
Emerging roles and mechanisms of FOXC2 in cancer
T Wang, L Zheng, Q Wang, YW Hu - Clinica chimica acta, 2018 - Elsevier
Forkhead box protein C2 (FOXC2), a transcription factor of the forkhead/winged-helix family,
is required for embryonic and prenatal development. FOXC2 acts as a crucial modulator …
is required for embryonic and prenatal development. FOXC2 acts as a crucial modulator …