Hepatocellular carcinoma (HCC), presently the second leading cause of global cancer‐
related mortality, continues to pose significant challenges in the realm of medical oncology …

Diisobutyl phthalate (DiBP) is a commonly used plasticizer in manufacturing consumer and
industrial products to improve flexibility and durability. Despite of the numerous studies …

Background Neuroinflammation mediated by microglial pyroptosis is an important
pathogenic mechanism of septic encephalopathy (SAE). It has been reported that TRIM45 is …

Macrophages are involved in the pathogenesis of allergic rhinitis (AR), but how these
macrophages are polarized to M1 or M2 type is undetermined. Long non-coding RNA …

Mycobacterium tuberculosis, a lethal pathogen in human history, causes millions of deaths
annually, which demands the development of new concepts of drugs. Considering this fact …

Autophagy is a fundamental cellular metabolic process, whose main role is to remove
excess or damaged organelles and maintain the normal structural state of cells. Autophagy …

The accumulation of protein aggregates defines distinct, yet overlapping pathologies such
as Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and frontotemporal …

Introduction Depression is a common psychological disorder, accompanied by a
disturbance of the gut microbiota and its metabolites. Recently, microbiota-derived …

Background Depression is a common mental illness characterised by abnormal and
depressed emotions. Total paeony glycoside (TPG) is a naturally active saponin extracted …

Phthalate esters (PAEs) are primary plasticizers and endocrine-disrupting chemicals (EDCs)
that are extensively used in numerous everyday consumer products. Although the adverse …