[PDF][PDF] Regulation of development and differentiation by the extracellular matrix

JC Adams, FM Watt - Development, 1993 - researchgate.net
Regulation of development and differentiation by the extracellular matrix Page 1
INTRODUCTION Differentiation is a continuously regulated process and interactions between the …

Angiogenesis: a dynamic balance of stimulators and inhibitors

LM Iruela-Arispe, HF Dvorak - Thrombosis and haemostasis, 1997 - thieme-connect.com
Under the influence of specific cytokines, endothelial cells (EC) change from a quiescent
state in which cell cycling is measured in terms of years, to a rapidly replicating and highly …

Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene

K Kuno, N Kanada, E Nakashima, F Fujiki… - Journal of Biological …, 1997 - ASBMB
A cellular disintegrin and metalloproteinase (ADAM) is a new family of genes with structural
homology to the snake venom metalloproteinases and disintegrins. We screened genes …

[HTML][HTML] Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements.

A Krikos, CD Laherty, VM Dixit - Journal of Biological Chemistry, 1992 - Elsevier
A20 was first identified as a tumor necrosis factor (TNF) primary response transcript
encoding a 790-amino acid protein with a unique zinc finger motif. Recently, A20 was shown …

Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density …

TR Kyriakides, YH Zhu, LT Smith, SD Bain… - The Journal of cell …, 1998 - rupress.org
Thrombospondin (TSP) 2, and its close relative TSP1, are extracellular proteins whose
functions are complex, poorly understood, and controversial. In an attempt to determine the …

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

C Leung-Hagesteijn, AM Spence, BD Stern, Y Zhou… - Cell, 1992 - cell.com
The uric-5 gene is required for guiding pioneering axons and migrating ceils along the body
wail in C. eiegans. In mutants, dorsal migrations are disrupted, but ventral and longitudinal …

F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension

A Klar, M Baldassare, TM Jessell - Cell, 1992 - cell.com
The floor plate is a cell group implicated in the control of neural cell pattern and axonal
growth in the developing vertebrate nervous system. To identify molecules that might …

Thrombospondins function as regulators of angiogenesis

P Bornstein - Journal of cell communication and signaling, 2009 - Springer
Abstract Thrombospondins (TSPs)-1 and-2 were among the first protein inhibitors of
angiogenesis to be identified, a property that was subsequently attributed to the interactions …

Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis

M Streit, L Riccardi, P Velasco… - Proceedings of the …, 1999 - National Acad Sciences
Recent evidence suggests a potential role for thrombospondin-2 (TSP-2), a matricellular
glycoprotein, in the regulation of primary angiogenesis. To directly examine the biological …

[HTML][HTML] COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins.

A Oldberg, P Antonsson, K Lindblom… - Journal of Biological …, 1992 - Elsevier
Cloning and sequence analysis of cartilage oligomeric matrix protein (COMP) cDNA,
representing a cartilage pentameric protein, revealed a protein of 755 amino acid residues …