The human circulatory system is a marvelous fluidic system, which is very sensitive to
biophysical and biochemical cues. The current animal and cell culture models do not …

Introduction Organ-on-a-chip (OOC) models are based on microfluidics and can recapitulate
the healthy and diseased microstructure of organs1 and tissues and the dynamic …

Platelets play vital roles in vascular repair, especially in primary hemostasis, and have been
widely used in transfusion to prevent bleeding or manage active bleeding. Recently …

The mortality rate of patients with critical illness has decreased significantly over the past two
decades, but the rate of decline has slowed recently, with organ dysfunction as a major …

Red blood cells (RBCs) passing through heart pumps, prosthetic heart valves and other
cardiovascular devices undergo early senescence attributed to non-physiologic forces. We …

This study advances microfluidic probe (MFP) technology through the development of a 3D-
printed Microfluidic Mixing Probe (MMP), which integrates a built-in pre-mixer network of …

Microparticles are produced by various cells due to a number of different stimuli in the
circulatory system. Shear stress has been shown to injure red blood cells resulting in …

A critical role of the peripheral axons of nociceptors of the dorsal root ganglion (DRG) is the
conduction of all-or-nothing action potentials from peripheral nerve endings to the central …

We employ a three-dimensional numerical model to analyze the dynamics of single-phase
flow in a parallel branched microchannel with varying geometric dimensions of constrictions …

The shape of a microchannel during flow through it is instrumental to understanding the
physics that govern various phenomena ranging from rheological measurements of fluids to …