The adaptive immune response is a major determinant of the clinical outcome after SARS- CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …
R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant (B. 1.1. 529) has multiple spike protein mutations, that contribute to viral escape from antibody neutralization,,–and reduce vaccine …
We address whether T cell responses induced by different vaccine platforms (mRNA-1273, BNT162b2, Ad26. COV2. S, and NVX-CoV2373) cross-recognize early SARS-CoV-2 …
The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B. 1.1. 529) variant of concern (VOC) has destabilized global efforts to control the …
A Sette, S Crotty - Immunological reviews, 2022 - Wiley Online Library
Immunological memory is the basis of protective immunity provided by vaccines and previous infections. Immunological memory can develop from multiple branches of the …
Background Few data exist on the comparative safety and immunogenicity of different COVID-19 vaccines given as a third (booster) dose. To generate data to optimise selection …
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel spike protein mutations that are influencing the epidemiological and clinical aspects of the …
D Goldblatt, G Alter, S Crotty… - Immunological reviews, 2022 - Wiley Online Library
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐ CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …