Recent developments of diazo compounds in organic synthesis
D Qiu, J Wang - 2021 - World Scientific
Diazo compounds are versatile organic compounds and have become increasingly
important in organic synthesis and many other fields. In particular, α-diazocarbonyl …
important in organic synthesis and many other fields. In particular, α-diazocarbonyl …
Cycloaddition/annulation strategies for the construction of multisubstituted pyrrolidines and their applications in natural product synthesis
J Li, Y Ye, Y Zhang - Organic Chemistry Frontiers, 2018 - pubs.rsc.org
Pyrrolidines are privileged substructures of numerous bioactive natural products and drugs.
How to synthesize these important synthetic targets in a more efficient manner is a hot …
How to synthesize these important synthetic targets in a more efficient manner is a hot …
Convergent and Efficient Total Synthesis of (+)-Heilonine Enabled by C–H Functionalizations
We report a convergent and efficient total synthesis of the C-nor D-homo steroidal alkaloid
(+)-heilonine with a hexacyclic ring system, nine stereocenters, and a trans-hydrindane …
(+)-heilonine with a hexacyclic ring system, nine stereocenters, and a trans-hydrindane …
Enantioselective Total Synthesis of (−)-Zygadenine
Y Guo, JT Lu, R Fang, Y Jiao, J Liu… - Journal of the American …, 2023 - ACS Publications
The Veratrum alkaloids are highly complex steroidal alkaloids characterized by their intricate
structural and stereochemical features and exhibit a diverse range of pharmacological …
structural and stereochemical features and exhibit a diverse range of pharmacological …
One-pot double [3+ 2] cycloadditions for diastereoselective synthesis of pyrrolidine-based polycyclic systems
Sequential inter-and intramolecular [3+ 2] cycloadditions of azomethine ylides are
developed for the one-pot and diastereoselective synthesis of highly condensed …
developed for the one-pot and diastereoselective synthesis of highly condensed …
The Veratrum and Solanum alkaloids
P Heretsch, A Giannis - The Alkaloids: Chemistry and Biology, 2015 - Elsevier
This survey on steroidal alkaloids of the Veratrum and Solanum family isolated between
1974 and 2014 includes 187 compounds and 197 references. New developments in the …
1974 and 2014 includes 187 compounds and 197 references. New developments in the …
Formal and total synthesis of (±)-cycloclavine
ND Jabre, T Watanabe, M Brewer - Tetrahedron letters, 2014 - Elsevier
A ring fragmentation and intramolecular azomethine ylide 1, 3-dipolar cycloaddition
sequence of reactions was successfully used in the preparation of a known (±)-cycloclavine …
sequence of reactions was successfully used in the preparation of a known (±)-cycloclavine …
Synthesis of 5α, 6-Dihydroveragranines A and B
LC Zhu, DL Yang, Y Shi - Organic Letters, 2022 - ACS Publications
The 5α, 6-dihydro congeners of veragranines A and B, two steroidal alkaloids with an
unprecedented hexacyclic skeleton and potent analgesic effects, were synthesized from …
unprecedented hexacyclic skeleton and potent analgesic effects, were synthesized from …
Novel d-Annulated Pentacyclic Steroids: Regioselective Synthesis and Biological Evaluation in Breast Cancer Cells
SK Vorontsova, AV Yadykov, AM Scherbakov… - Molecules, 2020 - mdpi.com
The acid-catalyzed cyclization of benzylidenes based on 16-dehydropregnenolone acetate
(16-DPA) was studied. It was found that these compounds readily undergo regioselective …
(16-DPA) was studied. It was found that these compounds readily undergo regioselective …
Alkynogenic fragmentation
J Yang, TT Hoang, GB Dudley - Organic Chemistry Frontiers, 2019 - pubs.rsc.org
Fragmentation reactions in synthetic organic chemistry involve substrates breaking into
three or more pieces (fragments), adding degrees of unsaturation into two or more parts …
three or more pieces (fragments), adding degrees of unsaturation into two or more parts …