While in the past technology has mostly been utilized to store information about the
structural configuration of proteins and molecules for research and medical purposes …

With the modern quality, quantity, and availability of genomic sequencing across species, as
well as across the expanse of human populations, we can screen for shared signatures …

Although molecular features underlying aging and species maximum lifespan (MLS) have
been comprehensively studied by transcriptome analyses, the actual impact of transcriptome …

Femoral atherosclerotic plaques are less inflammatory than carotid plaques histologically,
but limited cell-level data exist regarding comparative immune landscapes and polarization …

Major depressive disorder (MDD) and substance-use disorders (SUDs) often lead to
premature aging, increasing vulnerability to cognitive decline and other forms of dementia …

Tissue fibrosis is a major driver of pathology in aging and is involved in numerous age-
related diseases. The lungs are particularly susceptible to fibrotic pathology which is …

Genetic manipulations can ameliorate the aging process and extend the lifespan of model
organisms. The aim of this research was to identify novel genetic interventions that promote …

Integrative genomics embodies a collaborative approach that brings together various
disciplines, merging genomic and computational methodologies to achieve a …

Two of the most critical stages in early development occur during the maturation of oocytes
and during the first lineage specification during morula-to-blastocyst transition. The accurate …

There are mammals that have exceptionally long lifespans when compared to closely
related species in the phylogenetic tree. This suggest that relatively small variations in the …