Combining nanotechnology with monoclonal antibody drugs for rheumatoid arthritis treatments

XK Chi, XL Xu, BY Chen, J Su, YZ Du - Journal of Nanobiotechnology, 2023 - Springer
Rheumatoid arthritis (RA) is a systemic immune disease characterized by synovial
inflammation. Patients with RA commonly experience significant damage to their hand and …

Recent advances on emerging nanomaterials for diagnosis and treatment of inflammatory bowel disease

W Fu, L Xu, Z Chen, L Kan, Y Ma, H Qian… - Journal of Controlled …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic idiopathic inflammatory disorder that affects
the entire gastrointestinal tract and is associated with an increased risk of colorectal cancer …

[HTML][HTML] Lipid-and polymer-based formulations containing TNF-α inhibitors for the treatment of inflammatory bowel diseases

S Voci, A Gagliardi, N Ambrosio, A Zannetti… - Drug Discovery …, 2024 - Elsevier
Monoclonal antibodies inhibiting tumor necrosis factor-alpha (iTNF-α) have revolutionized
the therapeutic regimen of inflammatory bowel disease, but their main drawback is the …

Nanoparticle-Based Drug Delivery Systems Enhance Treatment of Cognitive Defects

G Wilar, C Suhandi, N Wathoni… - International Journal …, 2024 - Taylor & Francis
Nanoparticle-based drug delivery presents a promising solution in enhancing therapies for
neurological diseases, particularly cognitive impairment. These nanoparticles address …

Active nanoparticle targeting of MUC5AC ameliorates therapeutic outcome in experimental colitis

B Riemann, T Antoine, A Béduneau, Y Pellequer… - Nanoscale, 2024 - pubs.rsc.org
Inflammatory bowel diseases (IBDs), which include Crohn's disease (CD) and ulcerative
colitis (UC), are chronic inflammatory diseases of the gastrointestinal tract and are …

Co-formulations of adalimumab with hyaluronic acid/polyvinylpyrrolidone to combine intraarticular drug delivery and viscosupplementation

T Siefen, S Bjerregaard, D Plaksin, J Lokhnauth… - European Journal of …, 2022 - Elsevier
Polymer-based formulations present an attractive strategy in intraarticular drug-delivery to
refrain biologicals from early leakage from the joint. In this study, co-formulations of …

[HTML][HTML] Advancements in Inflammatory Bowel Disease Management: From Traditional Treatments to Monoclonal Antibodies and Future Drug Delivery Systems

A Di Rienzo, L Marinelli, MP Dimmito, EC Toto… - Pharmaceutics, 2024 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disorder with
two main subtypes: ulcerative colitis (UC) and Crohn's disease (CD). The pathogenesis …

Development of nanoparticle‐based drug delivery system for inflammation treatment and diagnosis

Q Qin, M Wang, Y Zou, D Yang, Y Deng… - MedComm …, 2023 - Wiley Online Library
Inflammation is a prevalent pathological process that accompanies the onset and
progression of numerous acute and chronic diseases including rheumatoid arthritis, sepsis …