Viruses of archaea represent one of the most enigmatic parts of the virosphere. Most of the
characterized archaeal viruses infect extremophilic hosts and display remarkable diversity of …

No longer considered to be exclusive to cellular developmental pathways, the Wnt family of
secreted cysteine-rich glycosylated proteins has emerged as versatile targets for a variety of …

Acute as well as chronic disorders of the nervous system lead to significant morbidity and
mortality for millions of individuals globally. Given the ability to govern stem cell proliferation …

Oxidative stress significantly impacts multiple cellular pathways that can lead to the initiation
and progression of varied disorders throughout the body. It therefore becomes imperative to …

Viruses populate virtually every ecosystem on the planet, including the extreme acidic,
thermal, and saline environments where archaeal organisms can dominate. For example …

Unmitigated oxidative stress can lead to diminished cellular longevity, accelerated aging,
and accumulated toxic effects for an organism. Current investigations further suggest the …

The successful treatment for multiple disease entities can rest heavily upon the ability to
elucidate the intricate relationships that govern cellular proliferation, metabolism, survival …

The daily production of 200 billion erythrocytes requires 20 mg of iron, accounting for nearly
80% of the iron demand in humans. Thus, erythroid precursor cells possess an efficient …

Given that erythropoietin (EPO) is no longer believed to have exclusive biological activity in
the hematopoietic system, EPO is now considered to have applicability in a variety of …

Archaeal viruses are some of the most enigmatic viruses known, due to the small number
that have been characterized to date. The number of known archaeal viruses lags behind …