Novel role of COX6c in the regulation of oxidative phosphorylation and diseases

C Wang, J Lv, C Xue, J Li, Y Liu, D Xu, Y Jiang… - Cell death …, 2022 - nature.com
Cytochrome c oxidase subunit VIc (COX6c) is one of the most important subunits of the
terminal enzyme of the respiratory chain in mitochondria. Numerous studies have …

Mass spectrometry–based proteomics analysis of human substantia nigra from Parkinson's disease patients identifies multiple pathways potentially involved in the …

Y Jang, O Pletnikova, JC Troncoso, AY Pantelyat… - Molecular & Cellular …, 2023 - ASBMB
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
characterized by the loss of dopaminergic neurons in the substantia nigra (SN) of the brain …

Metabolism in the age of 'omes'

RK Suarez, CD Moyes - Journal of Experimental Biology, 2012 - journals.biologists.com
Much research in comparative physiology is now performed using 'omics' tools and many
results are interpreted in terms of the effects of changes in gene expression on energy …

Adaptive modifications of muscle phenotype in high-altitude deer mice are associated with evolved changes in gene regulation

GR Scott, TS Elogio, MA Lui, JF Storz… - … biology and evolution, 2015 - academic.oup.com
At high-altitude, small mammals are faced with the energetic challenge of sustaining
thermogenesis and aerobic exercise in spite of the reduced O2 availability. Under conditions …

Temperature during embryonic development has persistent effects on metabolic enzymes in the muscle of zebrafish

ME Schnurr, Y Yin, GR Scott - Journal of Experimental …, 2014 - journals.biologists.com
Global warming is intensifying interest in the physiological consequences of temperature
change in ectotherms, but we still have a relatively poor understanding of the effects of …

Proteomics revealed composition-and size-related regulators for hepatic impairments induced by silica nanoparticles

X Zhao, R Ma, A Abulikemu, Y Qi, X Liu, J Wang… - Science of The Total …, 2024 - Elsevier
Along with the growing production and application of silica nanoparticles (SiNPs), increased
human exposure and ensuing safety evaluation have progressively attracted concern …

New insight into the molting and growth in crustaceans: regulation of energy homeostasis through the lipid nutrition

Y Yuan, M Jin, F Fang, DR Tocher… - Frontiers in Marine …, 2022 - frontiersin.org
Organisms can regulate mitochondrial metabolic adaptation, further ameliorate the energy
homeostasis to control the ATP production for the energy expenditure during the growth …

Dietary lipid concentration affects liver mitochondrial DNA copy number, gene expression and DNA methylation in large yellow croaker (Larimichthys crocea)

K Liao, J Yan, K Mai, Q Ai - … and Physiology Part B: Biochemistry and …, 2016 - Elsevier
In response to changes in energy demand and nutrient supply, the organism regulates
mitochondrial metabolic status to coordinate ATP production. To survey mitochondrial …

Excess dietary zinc intake in neonatal mice causes oxidative stress and alters intestinal host–microbe interactions

A Podany, J Rauchut, T Wu… - Molecular nutrition & …, 2019 - Wiley Online Library
Scope Greater than 68% of young infants are exposed to dietary zinc (Zn) levels that are
higher than the Tolerable Upper Intake Limit. However, the consequences of excess dietary …

Sub-lethal toxicity assessment of the phenylurea herbicide linuron in developing zebrafish (Danio rerio) embryo/larvae

S Maharaj, N El Ahmadie, S Rheingold… - Neurotoxicology and …, 2020 - Elsevier
Due to run-off and rain events, agrochemicals can enter water catchments, exerting
endocrine disruption effects and toxicity to aquatic organisms. Linuron is a phenylurea …