Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation

AT Nies, E Schaeffeler, M Schwab - Pharmacology & Therapeutics, 2022 - Elsevier
Organic cation transporters (OCT), organic anion transporting polypeptides (OATP) and
organic anion transporters (OAT) from the solute carrier (SLC) family play an essential role …

The efficacy and safety of Chinese herbal medicine as an add-on therapy for type 2 diabetes mellitus patients with carotid atherosclerosis: an updated meta-analysis …

Z Zhang, Y Leng, Z Chen, X Fu, Q Liang… - Frontiers in …, 2023 - frontiersin.org
Background: Type 2 diabetes mellitus (T2DM) is a clinical metabolic syndrome
characterized by persistent hyperglycemia. Patients with T2DM are more likely to have …

[HTML][HTML] Metabolic Syndrome Drug Therapy: The Potential Interplay of Pharmacogenetics and Pharmacokinetic Interactions in Clinical Practice: A Narrative Review

S Knežević, F Filippi-Arriaga, A Belančić, T Božina… - Diabetology, 2024 - mdpi.com
Metabolic syndrome (MetS) presents a significant global health challenge, characterized by
a cluster of metabolic alterations including obesity, hypertension, insulin resistance …

The efficacy and safety of dachaihu decoction in the treatment of type 2 diabetes mellitus: A systematic review and meta-analysis

Z Zhang, Y Leng, X Fu, C Yang, H Xie… - Frontiers in …, 2022 - frontiersin.org
Background: Type 2 diabetes mellitus (T2DM) is a clinical metabolic syndrome
characterized by persistent hyperglycemia, which is caused by defective insulin secretion …

[HTML][HTML] The role of MicroRNA networks in tissue-specific direct and indirect effects of metformin and its application

Q Yang, G Wang, D Fang, X Gao, Y Liang… - Biomedicine & …, 2022 - Elsevier
Metformin is a first-line oral antidiabetic agent that results in clear benefits in relation to
glucose metabolism and diabetes-related complications. The specific regulatory details and …

Protective effects and mechanisms of opuntia polysaccharide in animal models of diabetes mellitus: A systematic review and meta-analysis

R Chen, K Ma, S Li, X Zhou, H Chen - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Opuntia speciesis used in traditional medicine to treat
diabetes mellitus (DM). Polysaccharide is one of the main components of Opuntia. Opuntia …

Study on the therapeutic effect and mechanism of Tangningtongluo Tablet on diabetic mice

Z Cai, X Hu, L Gui, M Qi, W Zhu, Y Ren, S Yang… - Journal of Diabetes and …, 2023 - Elsevier
Aims To investigate the therapeutic effects of Tangningtongluo Tablet on diabetic mice and
its mechanism. This study was established the scientific basis for the clinical application of …

[HTML][HTML] Metformin: Diverse molecular mechanisms, gastrointestinal effects and overcoming intolerance in type 2 Diabetes Mellitus: A review

S Mohamed - Medicine, 2024 - journals.lww.com
Metformin, the first line treatment for patients with type 2 diabetes mellitus, has alternative
novel roles, including cancer and diabetes prevention. This narrative review aims to explore …

Precision medicine in diabetes

AY Dawed, E Haider, ER Pearson - Precision Medicine, 2022 - Springer
Tailoring treatment or management to groups of individuals based on specific clinical,
molecular, and genomic features is the concept of precision medicine. Diabetes is highly …

[PDF][PDF] Oral antidiabetic medications: technical notes

G Bereda - J Diabet Nephrop Diabetes Manag, 2022 - researchgate.net
An oral antidiabetic medication is the first line of medicine treatment for type 2 diabetes
mellitus. Biguanides are ancient agents that function by declining hepatic glucose output …