Platelet ageing is an area of research which has gained much interest in recent years.
Newly formed platelets, often referred to as reticulated platelets, young platelets or immature …

Platelet transfusions are routine procedures in clinical treatment aimed at preventing
bleeding in critically ill patients, including those with cancer, undergoing surgery, or …

Background Survivors of acute COVID-19 often suffer prolonged, diffuse symptoms post-
infection, referred to as “Long-COVID”. A lack of Long-COVID biomarkers and …

Cryopreservation of platelets, at− 80° C with 5–6% DMSO, results in externalisation of
phosphatidylserine and the formation of extracellular vesicles (EVs), which may mediate …

Platelet-producing megakaryocytes (MKs) primarily reside in the bone marrow, where they
duplicate their DNA content with each cell cycle resulting in polyploid cells with an intricate …

Receptor diffusion plays an essential role in cellular signalling via the plasma membrane
microenvironment and receptor interactions, but the regulation is not well understood. To aid …

Research into the natural aging process of platelets has garnered much research interest in
recent years, and there have long been associations drawn between the proportion of newly …

Introduction The protein tyrosine phosphatase SHP2 (PTPN11) is a negative regulator of
glycoprotein VI (GPVI)-induced platelet signal under certain conditions. Clinical trials with …

Blood platelets are anucleate cells essential for normal blood hemostasis. To maintain a
normal platelet count of 150 000 to 400 000 per μL of blood, 1011 platelets must be …

Background The association between mean platelet volume (MPV) and mortality in patients
with cardiovascular disease has been demonstrated. However, the association between …