Salmonella Typhimurium and inflammation: a pathogen-centric affair

JE Galán - Nature Reviews Microbiology, 2021 - nature.com
Microbial infections are controlled by host inflammatory responses that are initiated by
innate immune receptors after recognition of conserved microbial products. As inflammation …

Assembly, structure, function and regulation of type III secretion systems

W Deng, NC Marshall, JL Rowland… - Nature Reviews …, 2017 - nature.com
Type III secretion systems (T3SSs) are protein transport nanomachines that are found in
Gram-negative bacterial pathogens and symbionts. Resembling molecular syringes, T3SSs …

EffectorP 3.0: prediction of apoplastic and cytoplasmic effectors in fungi and oomycetes

J Sperschneider, PN Dodds - Molecular plant-microbe …, 2022 - Am Phytopath Society
Many fungi and oomycete species are devasting plant pathogens. These eukaryotic
filamentous pathogens secrete effector proteins to facilitate plant infection. Fungi and …

Engineering broad-spectrum bacterial blight resistance by simultaneously disrupting variable TALE-binding elements of multiple susceptibility genes in rice

Z Xu, X Xu, Q Gong, Z Li, Y Li, S Wang, Y Yang, W Ma… - Molecular plant, 2019 - cell.com
Xanthomonas oryzae pv. oryzae (Xoo), the causal agent of bacterial blight of rice, employs
the transcription activator-like effectors (TALEs) to induce the expression of the OsSWEET …

The age of coumarins in plant–microbe interactions

IA Stringlis, R De Jonge… - Plant and Cell Physiology, 2019 - academic.oup.com
Coumarins are a family of plant-derived secondary metabolites that are produced via the
phenylpropanoid pathway. In the past decade, coumarins have emerged as iron-mobilizing …

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

TRD Costa, C Felisberto-Rodrigues, A Meir… - Nature Reviews …, 2015 - nature.com
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …

Genetic modification to improve disease resistance in crops

HP Van Esse, TL Reuber, D van der Does - New Phytologist, 2020 - Wiley Online Library
Plant pathogens are a significant challenge in agriculture despite our best efforts to combat
them. One of the most effective and sustainable ways to manage plant pathogens is to use …

Emerging insights into molecular mechanisms underlying pyroptosis and functions of inflammasomes in diseases

F Lu, Z Lan, Z Xin, C He, Z Guo… - Journal of cellular …, 2020 - Wiley Online Library
Pyroptosis is a form of necrotic and inflammatory programmed cell death, which could be
characterized by cell swelling, pore formation on plasma membranes, and release of …

Petroleum hydrocarbon contamination in terrestrial ecosystems—fate and microbial responses

A Truskewycz, TD Gundry, LS Khudur, A Kolobaric… - Molecules, 2019 - mdpi.com
Petroleum hydrocarbons represent the most frequent environmental contaminant. The
introduction of petroleum hydrocarbons into a pristine environment immediately changes the …

Protein-injection machines in bacteria

JE Galán, G Waksman - Cell, 2018 - cell.com
Many bacteria have evolved specialized nanomachines with the remarkable ability to inject
multiple bacterially encoded effector proteins into eukaryotic or prokaryotic cells. Known as …