Ceramides are signals of fatty acid excess that accumulate when a cell's energetic needs
have been met and its nutrient storage has reached capacity. As these sphingolipids accrue …

Abstract Background Circular RNAs (circRNAs) play important roles in many biological
processes. However, the detailed mechanism underlying the critical roles of circRNAs in …

In addition to environmental conditions, lifestyle factors, and chemical exposure, aberrant
gene expression and mutations involve in the beginning and development of urological …

Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that is characterized by
unexplained segmental hypertrophy that is usually most pronounced in the septum. While …

Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that limits viral
pathogenesis and exerts poorly understood immunoregulatory functions. Here, using human …

Distant metastasis remains the major cause for treatment failure in patients with
nasopharyngeal carcinoma (NPC). Thus, it is necessary to investigate the underlying …

Background Glioma is the most commonly diagnosed malignant and aggressive brain
cancer in adults. Traditional researches mainly explored the expression profile of glioma at …

Aim To understand potential pro-oncological effects of lower dose paclitaxel treatment in
cervical cancer cells, we investigated the potential roles of KRT17 on migration and …

The adipose tissue (AT) surrounding breast cancer (BC) plays a pivotal role in cancer
progression and represents an optimal source for new biomarker discovery. The aim of this …

Proteomics analysis of circulating exosomes derived from cancer cells represents a
promising approach to the elucidation of cell–cell communication and the discovery of …