Chagas disease is an important neglected disease that affects 6–7 million people
worldwide. The disease has two phases: acute and chronic, in which there are different …

Emerging results indicate that an uncontrolled host immune response, leading to a life-
threatening condition called cytokine release syndrome (also termed “cytokine storm”), is the …

Impaired immune responses have been observed in patients with type-2 diabetes mellitus
(T2DM), which increases susceptibility to tuberculosis infection. However, the effect of the …

Chronic cardiomyopathy is the main clinical manifestation of Chagas disease (CD), a
disease caused by Trypanosoma cruzi infection. A hallmark of chronic chagasic …

Signaling through the mechanistic target of rapamycin complex 1 (mTORC1) is a major
regulatory node of pro‐inflammatory mediator production by macrophages (MΦs). However …

The innate immune response is an important host primary defense system against
pathogens. γ-Oryzanol is one of the nutritionally important phytoceutical components in rice …

Rabies virus (RABV), the causative agent for rabies disease is still presenting a major public
health concern causing approximately 60,000 deaths annually. This neurotropic virus …

Objectives: Chemokines play a key role in immune regulation and response, and have been
implicated in the pathogenesis of tuberculosis (TB). In this study, we investigated whether …

Crimean‐Congo hemorrhagic fever infection (CCHF) is a viral zoonosis. The pathogenesis
of this disease has not been established so far, however, cytokines account for its …

ABSTRACT Monocyte chemoattractant protein 1 (MCP-1) plays an important role in the
development of periodontitis. The purpose of this investigation was to evaluate association …