Ewing sarcoma (ES) is an aggressive sarcoma of bone and soft tissue occurring at any age
with a peak incidence in adolescents and young adults. The treatment of ES relies on a …

Common malignant tumors of the musculoskeletal system in children, adolescents, and
young adults (< 30 years old) include rhabdomyosarcoma, osteosarcoma, and Ewing's …

Acclaimed by the worldwide medical community as" a staple reference text in the medical
oncologist's library"(JAMA), DeVita, Hellman, and Rosenberg's Cancer: Principles and …

Background Synovial sarcomas account for up to 10 percent of soft-tissue sarcomas and
include two major histologic subtypes, biphasic and monophasic, defined respectively by the …

Synovial sarcomas are aggressive spindle cell sarcomas containing in some cases areas of
epithelial differentiation. They consistently show a specific t (X; 18; p11; q11), which usually …

Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

The Ewing family of tumors (Ewing's sarcoma and primitive neuroectodermal tumor [PNET])
is the second most common malignant bone tumor (after osteogenic sarcoma) in children …

PURPOSE More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1
genes, due to the t (11; 22)(q24; q12) translocation. At the molecular level, the EWS-FLI1 …

Translocated in liposarcoma, Ewing's sarcoma and TATA-binding protein-associated factor
15 constitute an interesting and important family of proteins known as the TET proteins. The …

Abstract Purpose: A specific TLS-CHOP fusion gene resulting from the t (12; 16) is present in
at least 95% of myxoid liposarcomas (MLS). Three common forms of the TLS-CHOP fusion …