Tumor-associated macrophages are an abundant cell type in the tumor microenvironment.
These macrophages serve as a promising target for treatment of cancer due to their roles in …

Abstract Purpose of Review In this review, we highlight the most important cellular and
molecular mechanisms that contribute to cardiac inflammation and fibrosis. We also discuss …

The skin is an organ harboring several types of immune cells that participate in innate and
adaptive immune responses. The immune system of the skin comprises both skin cells and …

The immunosuppressive activity of mesenchymal stromal cells (MSCs) in graft versus host
disease (GvHD) is well-documented, but their therapeutic benefit is rather unpredictable …

Macrophages play an integral role in host defenses against intracellular bacterial
pathogens. A remarkable plasticity allows for adaptation to the needs of the host to …

Leprosy is an infectious disease that may present different clinical forms depending on host
immune response to Mycobacterium leprae. Several studies have clarified the role of …

Mycobacterium leprae, the causative agent of leprosy, is still actively transmitted in endemic
areas reflected by the fairly stable number of new cases detected each year. Recognizing …

Resident cardiac macrophages (rcMacs) are integral components of the myocardium where
they have key roles for tissue homeostasis and in response to inflammation, tissue injury …

Leprosy is a chronic infectious disease whose evolution involves complex immune
mechanisms of the host that influence the clinical presentation of the disease. For many …

The development of high-throughput single-cell RNA-sequencing (scRNA-Seq)
methodologies has empowered the characterization of complex biological samples by …