Abstract Cyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers
exerting a pleiotropic and multifaceted role in genesis or promotion of carcinogenesis and …

Colorectal cancer is the third common cancer in this world, accounting for more than 1
million cases each year. However, detailed etiology and mechanism of colorectal cancer …

Introduction: COX-2 is a key enzyme in the process of prostaglandins (PGs) synthesis. The
products of this enzyme could play a major role as the mediators of the inflammatory …

Cancer-associated fibroblasts (CAFs) are important components in breast tumors and
essential for tumor progression and metastasis. However, the role of epigenetic modification …

Within the last few decades, melatonin has increasingly emerged in clinical oncology as a
naturally occurring bioactive molecule with substantial anticancer properties and a …

Colorectal Cancer (CRC) is a most common digestive system malignant tumor. Despite
recent advance in CRC treatment, searching for efficient biomarker and individual treatment …

Abstract Prostaglandin-endoperoxide synthase 2 (PTGS2), a crucial enzyme in
prostaglandin synthesis, catalyzes the conversion of arachidonic acid to prostaglandins and …

The prevalence of colorectal cancer is increasing worldwide, and despite advances in
treatment, colorectal cancer (CRC) remains in the top three for mortality due to several …

Objective The aim of this study was to investigate the effects of different amounts of wheat
bran (WB) inclusion and postbiotics form by Saccharomyces cerevisiae and phytase co …

Oxaliplatin (Oxa) is the first-line chemotherapeutic drug for the treatment of colorectal cancer
(CRC). However, long-term Oxa chemotherapy can induce inflammation and increase the …