Official international association for therapeutic drug monitoring and clinical toxicology guideline: development and validation of dried blood spot–based methods for …

S Capiau, H Veenhof, RA Koster… - Therapeutic drug …, 2019 - journals.lww.com
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to
facilitate Therapeutic Drug Monitoring (TDM). To assure the quality of bioanalytical methods …

Is the hematocrit still an issue in quantitative dried blood spot analysis?

S Velghe, L Delahaye, CP Stove - Journal of pharmaceutical and …, 2019 - Elsevier
Hematocrit-related issues remain a major barrier for (regulatory) acceptance of the classical
dried blood spot (DBS) analysis in the bioanalytical and clinical field. Lately, many attempts …

[HTML][HTML] Dried blood spots for global health diagnostics and surveillance: opportunities and challenges

MD Lim - The American journal of tropical medicine and hygiene, 2018 - ncbi.nlm.nih.gov
There is increasing interest in using dried blood spot (DBS) cards to extend the reach of
global health and disease surveillance programs to hard-to-reach populations …

Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial

M Roca, MI Alcoriza, JC Garcia-Cañaveras… - Analytica Chimica Acta, 2021 - Elsevier
Metabolomics has become an invaluable tool for both studying metabolism and biomarker
discovery. The great technical advances in analytical chemistry and bioinformatics have …

Clinical feasibility of dried blood spots: analytics, validation, and applications

Y Enderle, K Foerster, J Burhenne - Journal of Pharmaceutical and …, 2016 - Elsevier
Dried blood spots (DBS) sampling and their specific advantages are becoming common in
analytical and clinical routine. Being first established for metabolic disorder screening in …

[HTML][HTML] Biological fluid microsampling for therapeutic drug monitoring: A narrative review

A Cafaro, M Conti, F Pigliasco, S Barco, R Bandettini… - Biomedicines, 2023 - mdpi.com
Therapeutic drug monitoring (TDM) is a specialized area of laboratory medicine which
involves the measurement of drug concentrations in biological fluids with the aim of …

A novel, nondestructive, dried blood spot-based hematocrit prediction method using noncontact diffuse reflectance spectroscopy

S Capiau, LS Wilk, MCG Aalders, CP Stove - Analytical Chemistry, 2016 - ACS Publications
Dried blood spot (DBS) sampling is recognized as a valuable alternative sampling strategy
both in research and in clinical routine. Although many advantages are associated with DBS …

Volumetric absorptive microsampling as an alternative tool for therapeutic drug monitoring of first-generation anti-epileptic drugs

S Velghe, CP Stove - Analytical and bioanalytical chemistry, 2018 - Springer
Dosage adjustment of anti-epileptic drugs by therapeutic drug monitoring (TDM) is very
useful, especially for the first-generation anti-epileptic drugs (AEDs). Microsampling—the …

Microsampling: considerations for its use in pharmaceutical drug discovery and development

N Spooner, KD Anderson, J Siple, ER Wickremsinhe… - Bioanalysis, 2019 - Taylor & Francis
There is growing interest in the implementation of microsampling approaches for the
quantitation of circulating concentrations of analytes in biological samples derived from …

Quantitative determination of opioids in whole blood using fully automated dried blood spot desorption coupled to on‐line SPE‐LC‐MS/MS

R Verplaetse, J Henion - Drug testing and analysis, 2016 - Wiley Online Library
Opioids are well known, widely used painkillers. Increased stability of opioids in the dried
blood spot (DBS) matrix compared to blood/plasma has been described. Other benefits …