Abstract 'A disintegrin and metalloproteases'(ADAMs) are a family of transmembrane
proteins with diverse functions in multicellular organisms. About half of the ADAMs are active …

Neural crest cells are highly migratory cells that give rise to many derivatives including
peripheral ganglia, craniofacial structures and melanocytes. Neural crest cells migrate along …

Our increasing comprehension of neural crest cell development has reciprocally advanced
our understanding of cadherin expression, regulation, and function. As a transient …

The neural crest is the name given to the strip of cells at the junction between neural and
epidermal ectoderm in neurula‐stage vertebrate embryos, which is later brought to the …

The mammalian skull vault is a highly regulated structure that evolutionally protects brain
growth during vertebrate development. It consists of several membrane bones with different …

Since the time of Darwin, biologists have sought to understand the origins and maintenance
of life's diversity of form. However, the nature of the exact DNA mutations and molecular …

Neural crest cells have the extraordinary task of building much of the vertebrate body plan,
including the craniofacial cartilage and skeleton, melanocytes, portions of the heart, and the …

The cranial neural crest (CNC) is a highly motile population of cells that is responsible for
forming the face and jaw in all vertebrates and perturbing their migration can lead to …

Introduction: The Six1 transcription factor plays important roles in the development of cranial
sensory organs, and point mutations underlie craniofacial birth defects. Because Six1's …

The Eph/ephrin signalling pathways have a critical function in cell adhesion and repulsion,
and thus play key roles in various morphogenetic events during development. Here we …