The scientific study of human hookworm infection began at the dawn of the twentieth
century. In recent years, there have been dramatic improvements in our understanding of …

Hookworms infect perhaps one-fifth of the entire human population, yet little is known about
their interaction with our immune system. The two major species are Necator americanus …

The oomycetes form one of several lineages within the eukaryotes that independently
evolved a parasitic lifestyle and consequently are thought to have developed alternative …

To attempt description of the set of mRNA and protein (sialome) expressed in the salivary
glands of the tick Ixodes scapularis, we randomly sequenced 735 clones of a full-length …

Host-parasite interactions exert strong selection pressures on the genomes of both host and
parasite. These interactions can lead to negative frequency-dependent selection, a form of …

The intestinal helminth parasite, Heligmosomoides polygyrus bakeri offers a tractable
experimental model for human hookworm infections such as Ancylostoma duodenale and …

Kunitz type proteins are an important group of ubiquitous protease inhibitors found spanning
the evolutionary tree from microbes to mammals. These proteins can have single or multiple …

Neutrophils are the key players in the innate immune system, being weaponized with
numerous strategies to eliminate pathogens. The production of extracellular traps is one of …

Background Parasitism is a major ecological niche for a variety of nematodes. Multiple
nematode lineages have specialized as pathogens, including deadly parasites of insects …

Hookworm infection is a major public health problem that threatens about 500 million people
throughout tropical areas of the world. Adult hookworms survive for many years in the host …