The impact of new and emerging agents on outcomes for febrile neutropenia: addressing clinical gaps

J Crawford, C Oswalt - Current Opinion in Oncology, 2023 - journals.lww.com
Multiple emerging agents show promise in decreasing the burden of CIN. Use of these
therapies will reduce access disparities and will improve outcomes for patients with cancer …

Unlocking the regenerative key: Targeting stem cell factors for bone renewal

G Karima, HD Kim - Journal of Tissue Engineering, 2024 - journals.sagepub.com
Stem cell factors (SCFs) are pivotal factors existing in both soluble and membrane-bound
forms, expressed by endothelial cells (ECs) and fibroblasts throughout the body. These …

ASCO policy statement on biosimilar and interchangeable products in oncology

G Rodriguez, J Mancuso, GH Lyman… - JCO Oncology …, 2023 - ascopubs.org
As the voice of cancer care clinicians and the patients they serve, ASCO has taken steps to
elevate awareness about biosimilar products and their use in oncology. In 2018, ASCO …

Trends in use of granulocyte colony-stimulating factor following introduction of biosimilars among adults with cancer and commercial or Medicare insurance from 2014 …

CY Wang, CD Heldermon, SM Vouri, H Park… - JAMA Network …, 2021 - jamanetwork.com
Importance The introduction of biosimilars and novel delivery devices between 2014 and
2019 may have changed the utilization of granulocyte colony-stimulating factors (G-CSF) …

Real-world cost–effectiveness of primary prophylaxis with G-CSF biosimilars in patients at intermediate/high risk of febrile neutropenia

P Cornes, J Kelton, R Liu, O Zaidi, J Stephens… - Future …, 2022 - Taylor & Francis
Background: Real-world data suggests superiority of pegfilgrastim (PEG) over filgrastim (FIL)
in reducing the incidence of chemotherapy-induced febrile neutropenia (FN), probably …

[HTML][HTML] Usability evaluation of a noninvasive neutropenia screening device (pointcheck) for patients undergoing cancer chemotherapy: mixed methods observational …

G Lamaj, A Pablo-Trinidad, I Butterworth, N Bell… - Journal of Medical …, 2022 - jmir.org
Background Patients with cancer undergoing cytotoxic chemotherapy face an elevated risk
of developing serious infection as a consequence of their treatment, which lowers their white …

Effectiveness of biosimilar pegfilgrastim in patients with multiple myeloma after high-dose melphalan and autologous stem cell transplantation

M Martino, M Gori, G Porto, M Pellicano, L Santoro… - Annals of …, 2023 - Springer
Multiple myeloma (MM) is the main indication for autologous stem cell transplantation
(ASCT). Novel supportive therapies (eg, granulocyte colony-stimulating factor) have …

Patient out-of-pocket and payer costs for pegfilgrastim originator vs biosimilars as primary prophylaxis of febrile neutropenia in the first cycle among a commercially …

CY Wang, H Park, CD Heldermon, SM Vouri… - Journal of Managed …, 2022 - jmcp.org
BACKGROUND: It is unknown whether using pegfilgrastim biosimilars is cost saving in a
real-world setting. OBJECTIVE: To compare medical costs including pegfilgrastim drug costs …

Provider perceptions of barriers to biosimilar utilization in community oncology practices

O Briggs, CM Brown, P Indurlal, JS Garey… - Journal of the American …, 2024 - Elsevier
Background Biosimilars reduce the burden of cost on patients and payers, and so doing,
increase access to life-saving care. However, biosimilar uptake in the US has been …

Risk of chemotherapy-induced febrile neutropenia in intermediate-risk regimens: Clinical and economic outcomes of granulocyte colony-stimulating factor prophylaxis

S Aslam, E Li, E Bell, L Lal, AJ Anderson… - Journal of Managed …, 2023 - jmcp.org
BACKGROUND: Chemotherapy-induced neutropenia increases the risk of febrile
neutropenia (FN) and infection with resultant hospitalizations, with substantial health care …