Pseudomonas aeruginosa is associated with several human infections, mainly related to
healthcare services. In the hospital, it is associated with resistance to several antibiotics …

Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Azithromycin (AZM) is a synthetic macrolide antibiotic effective against a broad range of
bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti …

Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …

Azithromycin is a macrolide antibiotic which inhibits bacterial protein synthesis, quorum-
sensing and reduces the formation of biofilm. Accumulating effectively in cells, particularly …

Macrolides are among the most widely prescribed broad spectrum antibacterials, particularly
for respiratory infections. It is now recognized that these drugs, in particular azithromycin …

Background Macrolide resistance is an increasing problem; there is therefore debate about
when to implement maintenance treatment with macrolides in patients with chronic …

Air− liquid interface (ALI) culture models currently represent a valid instrument to recreate
the typical aspects of the respiratory tract in vitro in both healthy and diseased state. They …

Driven in part by its metabolic versatility, high intrinsic antibiotic resistance, and a large
repertoire of virulence factors, Pseudomonas aeruginosa is expertly adapted to thrive in a …

Pseudomonas aeruginosa is a leading cause of chronic respiratory infections in people with
cystic fibrosis (CF), bronchiectasis or chronic obstructive pulmonary disease (COPD), and …