Once focused mainly on the characterization of neoplasms, immunohistochemistry (IHC)
today is used in the investigation of a broad range of disease processes with applications in …

Advances in genomics, proteomics and molecular pathology have generated many
candidate biomarkers with potential clinical value. Their use for cancer staging and …

High-throughput and high-content databases are increasingly important resources in
molecular medicine, systems biology, and pharmacology. However, the information usually …

Immunohistochemistry is an integral technique in many veterinary laboratories for diagnostic
and research purposes. In the last decade, the ability to detect antigens (Ags) in tissue …

This critical review evaluates progress toward viable point-of-care protein biomarker
measurements for cancer detection and diagnostics. The ability to measure panels of …

Purpose Conflicting results on prognostic factors for advanced epithelial ovarian cancer
(EOC) have been reported because of small sample size and heterogeneity of study …

Because most potential molecular markers and targets are proteins, proteomic profiling is
expected to yield more direct answers to functional and pharmacological questions than …

Recognition of molecular diversity of cell surface proteomes in disease is essential for the
development of targeted therapies. Progress in targeted therapeutics requires establishing …

Animal models and human studies have been useful in dissecting the molecular
mechanisms of renal disease and finding new disease targets; however, translation of these …

Cancer can be defined as a deregulation or hyperactivity in the ongoing network of
intracellular and extracellular signaling events. Reverse phase protein microarray …