Biological roles and mechanisms of circular RNA in human cancers

Q Tang, SS Hann - OncoTargets and therapy, 2020 - Taylor & Francis
Circular RNA (circRNA) is an intriguing class of RNA with covalently closed-loop structure
and is highly stable and conservative. As new members of the ncRNAs, the function …

Circular RNAs and gastrointestinal cancers: epigenetic regulators with a prognostic and therapeutic role

P Naeli, MH Pourhanifeh, MR Karimzadeh… - Critical reviews in …, 2020 - Elsevier
Both environmental and genetic factors are involved in the initiation and development of
gastrointestinal cancer. Covalent closed circular RNAs (circRNAs) are produced by a …

Emerging roles of circular RNAs in osteoporosis

W Chen, B Zhang, X Chang - Journal of Cellular and Molecular …, 2021 - Wiley Online Library
Osteoporosis is one bone disease characterized with skeletal impairment, bone strength
reduced and fracture risk enhanced. The regulation processes of bone metabolism are …

Circular RNA hsa_circ_0110389 promotes gastric cancer progression through upregulating SORT1 via sponging miR-127-5p and miR-136-5p

M Liang, W Yao, B Shi, X Zhu, R Cai, Z Yu, W Guo… - Cell Death & …, 2021 - nature.com
Increasing studies have found that circular RNAs (circRNAs) are aberrantly expressed and
play important roles in the occurrence and development of human cancers. However, the …

Homogenous multifunctional microspheres induce ferroptosis to promote the anti-hepatocarcinoma effect of chemoembolization

M Chen, J Li, G Shu, L Shen, E Qiao, N Zhang… - Journal of …, 2022 - Springer
Transcatheter arterial chemoembolization (TACE) is one of the main palliative therapies for
advanced hepatocellular carcinoma (HCC), which is also regarded as a promising …

Circular RNAs as the pivotal regulators of epithelial-mesenchymal transition in gastrointestinal tumor cells

RA Mahmoudian, I Akhlaghipour, M Lotfi… - … -Research and Practice, 2023 - Elsevier
Gastrointestinal (GI) cancers, as the most common human malignancies are always
considered one of the most important health challenges in the world. Late diagnosis in …

The function and mechanism of circular RNAs in gastrointestinal tumours

H Nie, Y Wang, Z Liao, J Zhou, C Ou - Cell proliferation, 2020 - Wiley Online Library
Gastrointestinal tumours are tumours that originate in the digestive tract and have extremely
high morbidity and mortality. The main categories include: oesophageal, gastric, and …

[HTML][HTML] Circular RNAs: implications of signaling pathways and bioinformatics in human cancer

F Hu, Y Peng, X Fan, X Zhang, Z Jin - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) form a class of endogenous single-stranded RNA transcripts that
are widely expressed in eukaryotic cells. These RNAs mediate post-transcriptional control of …

Dampening HOTAIR sensitizes the gastric cancer cells to oxaliplatin through miR‐195‐5p and ABCG2 pathway

Y Luo, X Lu, W Ma, Y Xiao, C Wei… - Journal of Cellular …, 2023 - Wiley Online Library
Long non‐coding RNAs (lncRNA) have an extensive role in the progression and
chemoresistance of gastric cancer (GC). Deeply study the regulatory role of lncRNAs could …

Circular RNAs in intervertebral disc degeneration: an updated review

D Xu, X Ma, C Sun, J Han, C Zhou, SH Wong… - Frontiers in Molecular …, 2022 - frontiersin.org
Low back pain, a common medical condition, could result in severe disability and inflict huge
economical and public health burden. Its pathogenesis is attributed to multiple etiological …