A better understanding of the inflammatory, procoagulant, and immunosuppressive aspects
of sepsis has contributed to rational therapeutic plans. This review considers optimal …

Severe sepsis and septic shock are as common and lethal as other acute life-threatening
conditions that emergency physicians routinely confront such as acute myocardial infarction …

Introduction Data on quality of life beyond 2 years after intensive care discharge are limited
and we aimed to explore this area further. Our objective was to quantify quality of life and …

Background Sepsis is a common, expensive and frequently fatal condition. There is an
urgent need for developing new therapies to further reduce severe sepsis‐induced mortality …

The incidence and prevalence of sepsis depend on the definitions and records that we use
and we may be underestimating their impact. Up to 60% of the cases come from the …

Objective: To determine the financial impact of a sepsis protocol designed for use in the
emergency department. Design: Retrospective analysis of a before-after study testing the …

Objective: To study long-term mortality, quality of life (QOL), quality-adjusted life years
(QALYs), and costs per QALY in an unselected intensive care unit (ICU) patient population …

PURPOSE: Severe sepsis is a leading cause of death in critically ill patients. We evaluated
cost and workload according to infection site, place and time of acquisition, and severity …

Objective: To determine the clinical and epidemiologic characteristics of patients with sepsis
admitted to hospitals in Victoria, Australia, including the incidence of sepsis and severe …

Severe sepsis remains both an important clinical challenge and an economic burden in
intensive care. An estimated 750 000 cases occur each year in the US alone (300 cases per …