Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Design and applications of man-made biomimetic fibrillar hydrogels

E Prince, E Kumacheva - Nature Reviews Materials, 2019 - nature.com
Many extracellular matrices (ECMs) have a filamentous architecture, which influences cell
growth and phenotype and imparts tissues with specific properties. Man-made fibrillar …

Directed endothelial cell morphogenesis in micropatterned gelatin methacrylate hydrogels

M Nikkhah, N Eshak, P Zorlutuna, N Annabi, M Castello… - Biomaterials, 2012 - Elsevier
Engineering of organized vasculature is a crucial step in the development of functional and
clinically relevant tissue constructs. A number of previous techniques have been proposed …

Endothelial progenitor cells for the vascularization of engineered tissues

EB Peters - Tissue Engineering Part B: Reviews, 2018 - liebertpub.com
Self-assembled microvasculature from cocultures of endothelial cells (ECs) and stromal
cells has significantly advanced efforts to vascularize engineered tissues by enhancing …

Matrix composition regulates three-dimensional network formation by endothelial cells and mesenchymal stem cells in collagen/fibrin materials

RR Rao, AW Peterson, J Ceccarelli, AJ Putnam… - Angiogenesis, 2012 - Springer
Co-cultures of endothelial cells (EC) and mesenchymal stem cells (MSC) in three-
dimensional (3D) protein hydrogels can be used to recapitulate aspects of vasculogenesis …

Transdermal regulation of vascular network bioengineering using a photopolymerizable methacrylated gelatin hydrogel

RZ Lin, YC Chen, R Moreno-Luna, A Khademhosseini… - Biomaterials, 2013 - Elsevier
The search for hydrogel materials compatible with vascular morphogenesis is an active area
of investigation in tissue engineering. One candidate material is methacrylated gelatin …

What is the biological and clinical relevance of fibrin?

RI Litvinov, JW Weisel - Seminars in thrombosis and …, 2016 - thieme-connect.com
As our knowledge of the structure and functions of fibrinogen and fibrin has increased
tremendously, several key findings have given some people a superficial impression that the …

Challenges and Future Perspectives in Modeling Neurodegenerative Diseases Using Organ‐on‐a‐Chip Technology

FM Pramotton, S Spitz, RD Kamm - Advanced Science, 2024 - Wiley Online Library
Neurodegenerative diseases (NDDs) affect more than 50 million people worldwide, posing
a significant global health challenge as well as a high socioeconomic burden. With aging …

Three-dimensional vascularized lung cancer-on-a-chip with lung extracellular matrix hydrogels for in vitro screening

S Park, TH Kim, SH Kim, S You, Y Jung - Cancers, 2021 - mdpi.com
Simple Summary The development of three-dimensional in vitro screening tools that mimic
the microenvironment of human organs is crucial to understand the mechanism and efficacy …

The delayed addition of human mesenchymal stem cells to pre-formed endothelial cell networks results in functional vascularization of a collagen–glycosaminoglycan …

TM McFadden, GP Duffy, AB Allen, HY Stevens… - Acta biomaterialia, 2013 - Elsevier
This paper demonstrates a method to engineer, in vitro, a nascent microvasculature within a
collagen–glycosaminoglycan scaffold with a view to overcoming the major issue of graft …