Many extracellular matrices (ECMs) have a filamentous architecture, which influences cell growth and phenotype and imparts tissues with specific properties. Man-made fibrillar …
Engineering of organized vasculature is a crucial step in the development of functional and clinically relevant tissue constructs. A number of previous techniques have been proposed …
Self-assembled microvasculature from cocultures of endothelial cells (ECs) and stromal cells has significantly advanced efforts to vascularize engineered tissues by enhancing …
Co-cultures of endothelial cells (EC) and mesenchymal stem cells (MSC) in three- dimensional (3D) protein hydrogels can be used to recapitulate aspects of vasculogenesis …
The search for hydrogel materials compatible with vascular morphogenesis is an active area of investigation in tissue engineering. One candidate material is methacrylated gelatin …
RI Litvinov, JW Weisel - Seminars in thrombosis and …, 2016 - thieme-connect.com
As our knowledge of the structure and functions of fibrinogen and fibrin has increased tremendously, several key findings have given some people a superficial impression that the …
Neurodegenerative diseases (NDDs) affect more than 50 million people worldwide, posing a significant global health challenge as well as a high socioeconomic burden. With aging …
Simple Summary The development of three-dimensional in vitro screening tools that mimic the microenvironment of human organs is crucial to understand the mechanism and efficacy …
TM McFadden, GP Duffy, AB Allen, HY Stevens… - Acta biomaterialia, 2013 - Elsevier
This paper demonstrates a method to engineer, in vitro, a nascent microvasculature within a collagen–glycosaminoglycan scaffold with a view to overcoming the major issue of graft …