Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular
metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …

Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Multidimensional analyses have demonstrated the presence of a unique tumor
microenvironment (TME) in liver cancer. Tumor‐associated macrophages (TAMs) are …

Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Abstract Anti–PD-1/PD-L1 immune checkpoint blockade (ICB) therapy has revolutionized
the treatment of many types of cancer over the past decade. The initial therapeutic …

Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

The most immune cells infiltrating tumor microenvironment (TME), tumor‐associated
macrophages (TAMs) closely resemble immunosuppressive M2‐polarized macrophages …

Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Rather than primary solid tumors, metastasis is one of the hallmarks of most cancer deaths.
Metastasis is a multistage event in which cancer cells escape from the primary tumor survive …